Burn Publications

Study examined the existing literature on burns to see if the differences between pediatric and adult calcemic and parathyroid hormone (PTH) responses to burn injury. The authors’ research has shown that children present with sustained hypocalcemia, hypomagnesemia, and hypoparathyroidism consistent with up-regulation of the parathyroid calcium-sensing receptor (CaSR) while adults ...

This review article describes the contributions of the Galveston P50 Research Center in Peri-Operative Sciences (RCIPS) that have changed post-burn care and have considerably reduced post-burn mortality. Since the inception of the P50 RCIPS funding mechanism, the National Institute for General Medical Sciences has supported a team approach to science. ...

Study assess the cardiovascular response to submaximal exercise in children nearly 1 year after burn injury. It was hypothesized that burn injury would lower cardiac output (Q) and stroke volume (SV) during submaximal exercise in burned children compared with non-burned healthy children matched for age and aerobic capacity. Five children ...

Article describes the development of a pool of items addressing the social impact of burn injuries in adults to create a self-reported computerized adaptive test based on item response theory. The authors conducted a comprehensive literature review to identify preexisting items in other self-reported measures and used data from ...

Dr. Basil A. Pruitt Jr., a consummate clinical and translational surgeon-scientist, has been spent over half a century at the forefront of an advancing standard of burn care. Commanding the United States Army Institute for Surgical Research in San Antonio, he trained generations of leading burn clinicians and allied scientists. ...

Study evaluated the short-term impact of the three antibiotic administration types on renal dysfunction. Vancomycin is a common antibiotic after burn injury and is administered alone (V), or in combination with imipenem-cilastin (V/IC) or piperacillin-tazobactam (V/PT). Sparse reports indicate that the combination V/PT is associated with increased renal dysfunction. All ...

Study investigated whether the coadministration of oxandrolone and propranolol alters plasma propranolol concentrations. Propranolol, is a beta blocker used to reduce resting heart rate and cardiac work caused by elevated circulating catecholamines. Oxandrolone, a testosterone mimetic, promotes protein synthesis and anabolism to counter muscle wasting; testosterone administration is known ...

This article calls for physicians to implement patient-reported outcome measures (PROMs) into their practice and for researchers to study their potential value in the clinical setting. PROMs are powerful tools that can bridge the need for data-driven patient information while also strengthening the physician-patient connection. When maximized in clinical ...

This article examines the output from each Burn Model System (BMS) component over the past 20 years. The National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR) established the BMS in 1993 to improve the lives of burn survivors. The BMS program includes: (1) a multicenter longitudinal database ...

Study examined the effect of scald burn injury on rat tracheal epithelium at 5 days after injury and tested the hypothesis that treatment with febuxostat (FBX), an inhibitor of xanthine oxidase (XO), can be protective of cell homeostasis. Sprague Dawley rats were randomly divided into uninjured (sham), injured (control), and ...

Article reviews current perspectives in the diagnosis and treatment of sepsis and septic shock in burn patients. Modern burn care has led to unprecedented survival rates in burn patients whose injuries were fatal a few decades ago. Along with improved survival, new challenges have emerged in the management of burn ...

Study investigated the effect of electrical burns on metabolic rate, body composition, and aerobic capacity in children with electrical burns. Twenty-four severely burned children were studied: 12 children had a combination of electrical and flame burns and 12 matched controls had only flame burns. Exercise assessments were conducted after ...

This systematic review examined clinical differences among subtypes of human herpes viruses, including herpes simplex virus (HSV), cytomegalovirus (CMV), and varicella zoster virus (VZV); described established therapy approaches, and assessed evidence of herpes virus-related morbidity and mortality in burn patients. PubMed, Ovid, and Web of Science were searched to ...

Study assessed the direct and long-term effects of transcranial direct current stimulation (tDCS) of the primary motor cortex (M1) on pain, quality of life (QOL), and life satisfaction following spinal cord injury (SCI). A two-phase randomized sham-controlled clinical trial was performed in which patients received 5 days of tDCS followed ...

Study evaluated the psychometric properties of the 4-dimension (4-D) itch scale, a modified version of the 5-dimension itch scale, in a sample of individuals with severe burn injury and/or burn injuries to hands, face, and/or feet. Four of the five domains of the 5-dimension itch scale (4-D) were administered ...

Study investigated whether the peripheral capillary oxygenation (Spo2)-to-Fio2 (S/F) ratio correlates with the Pao2/Fio2 (P/F) ratio in burned children with smoke inhalation injury (SII). The objective was to determine if the S/F ratio can serve as a surrogate for the P/F ratio for the diagnosis of acute respiratory distress syndrome ...

Study evaluated the utility of telemedicine during the rehabilitative phase of burn care. Telemedicine is defined as the use of information technology to deliver health care at a distance. A retrospective review was performed on patients enrolled in a program that utilized telemedicine between a burn center and rehabilitation ...

Study examined the extent to which the outcome measures for the Burn Injury Model Systems (BMS) collect data that encompass the entire experience of burn patients over time. Each meaningful concept included in the BMS assessments was linked to the International Classification of Functioning, Disability and Health (ICF) in ...

Study compared burn size estimations obtained with three-dimensional (3D) computer-aided software to those obtained with standard-of-care methods. Burn units have historically used paper diagrams to estimate percent burn; however, unintentional errors can occur. The use of a computer program that incorporates wound mapping from photographs onto a 3D human ...