Burn Publications

This review article discusses the epidemiology of burn infections, defines degrees of severity of infection, outlines the major organisms associated with burn wounds, and describes the specific organs and tissues susceptible to infection. The authors also discuss strategies for surveillance, sampling, and infection control in the burn intensive care ...

Study documents the long-term musculoskeletal complications following major burn injury. This is a cross-sectional descriptive study that includes a one-time evaluation of 98 burn survivors (mean age = 47 years; mean total body surface area burned = 57 percent; and mean time from injury = 17 years.) A comprehensive ...

Study examined the incidence and severity of contractures in a large, multicenter, burn population and determined the associated risk factors for the development of contractures. Data from the National Institute on Disability and Rehabilitation Research Burn Model System database, for adult burn survivors from 1994 to 2003, were analyzed. ...

This literature review summarizes the data supporting the prevalent role that β-adrenergic receptors play in mediating post-burn cardiac dysfunction and the idea that pharmacological modulation of this receptor family is a viable therapeutic target for resolving burn-induced cardiac deficits. Severe burn profoundly affects organs both proximal and distal to ...

This systematic review of the literature was conducted to identify evidence to support the use of measures of depression for adults with burn injuries. The goal was to determine the most reliable, valid, and efficient means of identifying adults with symptoms of depression including major depressive disorder. Established guidelines ...

Study investigated the effect of Clostridium difficile-associated diarrhea (CDAD) on morbidity and mortality in severely burned children and identified CDAD risk factors. After retrospective review of 2,840 records, 288 pediatric burn patients were identified as having diarrhea, defined as stool output of more than 10 milliliters per kilogram per ...

Article reviews the current understanding of the pathophysiology of smoke inhalation injury, the best evidence-based treatments, and challenges and future directions in diagnostics and management. Smoke inhalation injury is a serious medical problem that increases morbidity and mortality after severe burns. Despite recent advances in critical care and the ...

Study examined the effect of propranolol on hemodynamic parameters assessed using the PiCCO (Pulse index Continuous Cardiac Output) system in burned children. The study analyzed hemodynamic data from 121 patients who were randomized to receive either propranolol or placebo (control), which was initiated as a prospective randomized controlled trial. ...

The authors have previously described long-term outcomes related to the skin in patients surviving large burns. The objective of this study was to describe the long-term musculoskeletal complications following major burn injury. This is a cross-sectional descriptive study that includes a one-time evaluation of 98 burn survivors (mean age ...

Article discusses the psychometric properties and clinical utility of the Burn Outcome Questionnaires (BOQs). The BOQs are currently the most well-studied and clinically developed patient-reported outcome measures for use in children with burn injuries. There are currently four separate BOQ instruments: (1) the BOQ0–5, administered to the parents of ...

This is the first installment of a three-part series exploring the stress response to severe burn trauma. This article reviews the current literature pertaining to the pathophysiological stress response to burn trauma, and the leading therapies to mitigate this response. Focus will be placed on recent advances that have ...

Study compared cardiac output (CO) measurements performed in severely burned children using the transpulmonary thermodilution (TPTD) with the PiCCO (Pulse index Continuous Cardiac Output) system or transthoracic echocardiography (TTE). Fifty-four severely burned children were studied. Outcomes were compared using t-tests, multiple linear regression, and a Bland-Altman plot. An analysis ...

Study assessed the effects of gene expression or intracellular signaling in paralyzed muscles of men with long-standing spinal cord injury (SCI). Specifically, it examined the expression of genes (TNFαR, TNFα, IL-6R, IL-6, TWEAK, TWEAK R, atrogin-1, and MuRF1) and abundance of intracellular signaling proteins (TWEAK, TWEAK R, NF-κB, and p-p65/p-50/105) ...

Study examined the feasibility of a computerized, burn-specific patient-reported outcome measures, the Young Adult Burn Outcome Questionnaire (YABOQ), with real-time benchmarking feedback in a burn outpatient practice. The YABOQ was redesigned for formatting and presentation purposes, transcribed to a computerized format, and administered to young adult burn survivors via ...

Study compared long-term functional outcome between severely burned children who either participated or did not participate in a 12-week exercise program. A total of 125 severely burned children (mean age 12 years) who received no long-term anabolic drugs chose between a voluntary exercise program (EX-group) and no exercise (NoEX-group) ...

Study evaluated the efficacy of a 12-week community-based exercise training rehabilitation program (COMBEX) in improving lean mass, muscle strength, and aerobic capacity in children with severe burns. Thirty-four pediatric patients (aged 7–18 years) with burns covering 30 percent or more of their total body surface area (TBSA) were randomized ...

Study assessed the effects of exercise combined with whole-body vibration (WBV) on bone mass, lean mass (LM), and muscle strength in children recovering from burns. Nineteen children with ≥30 percent total body surface area (TBSA) burns were randomly assigned to a 6-week exercise regimen either alone (EX) or in ...

Study examines the incidence and severity of contractures in a large, multicenter, pediatric burn population and determined the associated risk factors for the development of contractures. Data from the National Institute on Disability and Rehabilitation Research Burn Model System database, for pediatric (younger than 18 years) burn survivors from ...

Study examined self-reported Satisfaction With Life Scale (SWLS) scores in a longitudinal, multicenter cohort of survivors of major burns and identified risk factors associated with SWLS scores are identified. The SWLS is a validated 5-item instrument with items rated on a 1-7 Likert scale. Data from the Burn Model ...