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Burn Publications

Publication Year
2011

Long-term oxandrolone treatment increases muscle protein net deposition via improving amino acid utilization in pediatric patients 6 months after burn injury

Study evaluated whether oxandrolone treatment affects mechanisms of protein turnover in skeletal muscle in response to amino acid (AA) infusion and on whole-body protein breakdown in pediatric burn patients 6 months postinjury. At the time of admission, patients were randomized to control or oxandrolone treatments. Clinically, oxandrolone has been ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2011

Children with burn injuries-assessment of trauma, neglect, violence and abuse

Article discusses the epidemiology and risk factors, mechanisms of injury, clinical assessment, and methods of prevention associated with pediatric burn injuries. Burns are the third most frequent cause of childhood injury resulting in death, behind motor vehicle accidents and drowning. Burn injuries account for the greatest length of stay ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2011

Virtual reality as an adjunctive non-pharmacologic analgesic for acute burn pain during medical procedures

Article reviews evidence from clinical and laboratory research studies exploring the use of virtual reality (VR) to control pain in burn patients undergoing painful medical procedures. VR analgesia has been demonstrated in burn patients both during daily wound care and during physical therapy. Burn patients report 35 to 50 ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2011

Functional genomics unique to week 20 post wounding in the deep cone/fat dome of the Duroc/Yorkshire porcine model of fibroproliferative scarring

Study reports the differential transcriptome over time and the functional genomics unique to Week 20 post wounding from the deep cones/fat domes in the Duroc/Yorkshire porcine model of fibroproliferative scarring following shallow and deep partial thickness wounds. A system was assembled that permits the study of genome-wide gene expression ...
Northwest Regional Burn Model System
Publication Year
2011

Measuring coping behavior in patients with major burn injuries: A psychometric evaluation of the BCOPE

Study assessed psychometric properties of the brief COPE (BCOPE) in hospitalized patients with burn injury. The BCOPE is a 28-item measure developed from the full-version COPE inventory (60 items) to provide an efficient means of assessing coping behaviors. A total of 362 participants admitted to the hospital with a ...
Johns Hopkins University Burn Injury Rehabilitation Model System
Publication Year
2011

Spatial and temporal localization of the melanocortin I receptor and its ligand a--melanocyte-stimulating hormone during cutaneous wound repair

Study investigated the role of the melanocortin 1 receptor (MC1R) and its ligand a-melanocyte-stimulating hormone (a-MSH) in the regulation of inflammatory and fibroproliferative responses to cutaneous injury. Specifically, the authors report the localization of the MC1R/a-MSH signaling in murine cutaneous wounds, human acute burns, and hypertrophic scars. During murine ...
Northwest Regional Burn Model System
Publication Year
2011

Psychiatric diagnoses after hospitalization with work-related burn injuries in Washington state

Study examined workers who were hospitalized with work-related burn injuries and their psychiatric sequelae in Washington State. Psychiatric sequelae of interest were depression, posttraumatic stress disorder, and other anxiety disorders. Workers' compensation claims for burn patients from Washington State hospitalized from January 2001 through April 2008 were identified. The ...
Northwest Regional Burn Model System
Publication Year
2010

Confirmatory Factor Analysis and Invariance of the Short Form McGill Pain Questionnaire (MPQ-SF) in a Longitudinal Sample of Burn Patients

Johns Hopkins University Burn Injury Rehabilitation Model System
Publication Year
2010

Growth curve trajectories of distress in burn patients

Psychological adjustment after a major burn injury is a significant concern to providers and patients alike. Although efforts have been made to identify associated risk factors, little is known about heterogeneity in the levels or trajectories of adjustment in this population. This study used a novel application of Growth ...
Johns Hopkins University Burn Injury Rehabilitation Model System
Publication Year
2010

Randomized Controlled Trial to Determine the Efficacy of Long-Term Growth Hormone Treatment in Severely Burned Children

Pediatric Burn Injury Rehabilitation Model System
Publication Year
2010

Extent and magnitude of catecholamine surge in pediatric burned patients

Increased catecholamine (CA) levels after severe burn are associated with stress, inflammation, hypermetabolism and impaired immune function. The CA secretion profiles in burned patients are not well described. Mechanisms, duration and extent of CA surge are unknown. The purpose of this large unicenter study was to evaluate the extent ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2010

The role of hyperglycemia in burned patients: evidence based studies”

Severely burned patients typically experience a systemic response expressed as increased metabolism, inflammation, alteration of cardiac and immune function, and associated hyperglycemia. Hyperglycemia has been associated with an increased risk of morbidity and mortality in critically ill patients. Until recently and for many years, hyperglycemia has been expectantly managed ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2010

Measurement of body composition in burned children: is there a gold standard?

Pediatric Burn Injury Rehabilitation Model System
Publication Year
2010

Posttraumatic stress disorder and pain impact functioning and disability after major burn injury

This study sought to clarify the prospective and concurrent associations of posttraumatic stress disorder (PTSD) and pain with functioning and disability after burn injury. The sample was composed of consecutive patients admitted to a regional burn center with major burn injuries (N = 171) who were followed at 1, ...
Johns Hopkins University Burn Injury Rehabilitation Model System
Publication Year
2010

Growth curve trajectories of distress in burn patients

Psychological adjustment after a major burn injury is a significant concern to providers and patients alike. Although efforts have been made to identify associated risk factors, little is known about heterogeneity in the levels or trajectories of adjustment in this population. This study used a novel application of Growth ...
Johns Hopkins University Burn Injury Rehabilitation Model System
Publication Year
2010

12-Year within-wound study of the effectiveness of custom pressure garment therapy

Pressure garment therapy is standard of care for prevention and treatment of hypertrophic scarring after burn injury. Nevertheless there is little objective data that confirms effectiveness. The purpose of this study was to determine the effectiveness of pressure garment therapy with objective data obtained with a randomized within-wound comparison. ...
Northwest Regional Burn Model System
Publication Year
2010

Association between Dietary Fat Content and Outcomes on pediatric Burn Patients (1)

BACKGROUND: The aim of the study was to compare a low fat/high-carbohydrate diet and a high-fat diet on clinical outcomes by a retrospective cohort study. METHODS: Nine hundred forty-four children with burns = 40% of their total body surface area (TBSA) were divided into two groups: patients receiving Vivonex ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2010

Donor site wound protein synthesis correlates with length of acute hospitalization in severely burned children

Autografting of burn wounds results in generation of donor site wounds. Here we measured donor site wound protein fractional synthesis rate (FSR) in a burn pediatric population and showed that FSR increases over time postsurgery and correlates with the length of hospital stay (LOS) normalized for total body surface ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2010

Sexual Attitudes and Behavior of Young Adults Who were Burned as Children

OBJECTIVE: Little is known about sexual attitudes and behaviors of adults burned as children. We hypothesized that survivors with large burn scars would have differences in sexual attitudes and behaviors from their unburned counterparts. METHODS: Ninety-two young adults (50 males and 42 females), ages 21.0 ± 2.7 years old, ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2010

Whole body protein kinetics measured with a non-invasive method in severely burned children

Persistent and extensive skeletal muscle catabolism is characteristic of severe burns. Whole body protein metabolism, an important component of this process, has not been measured in burned children during the long-term convalescent period. The aim of this study was to measure whole body protein turnover in burned children at ...
Pediatric Burn Injury Rehabilitation Model System

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Publication Year

  • 1996 (4)
  • 1998 (2)
  • 1999 (1)
  • 2000 (5)
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  • 2002 (7)
  • 2003 (12)
  • 2004 (10)
  • 2005 (9)
  • 2006 (19)
  • 2007 (40)
  • 2008 (23)
  • 2009 (25)
  • 2010 (38)
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  • 2013 (1)
  • 2014 (18)
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  • 2016 (31)
  • 2017 (20)
  • 2018 (10)
  • 2019 (12)
  • 2020 (10)
  • 2021 (3)
  • 2022 (1)

Participating Centers

  • Boston-Harvard Burn Injury Model System (63)
  • Georgia Model Brain Injury System (GAMBIS) (1)
  • Johns Hopkins University Burn Injury Rehabilitation Model System (46)
  • North Texas Burn Rehabilitation Model System (36)
  • Northwest Regional Burn Model System (83)
  • Pediatric Burn Injury Rehabilitation Model System (161)
  • Spaulding-Harvard Traumatic Brain Injury Model System (1)
  • UCHSC Burn Model System Data Coordination Center (BMS/DCC) (2)

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The contents of this site were developed under grant number 90DPKT0009 from the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR). NIDILRR is a Center within the Administration for Community Living (ACL), Department of Health and Human Services (HHS). The contents of this website do not necessarily represent the policy of NIDILRR, ACL, HHS, and you should not assume endorsement by the federal government.