Burn Publications

Study assessed the direct and long-term effects of transcranial direct current stimulation (tDCS) of the primary motor cortex (M1) on pain, quality of life (QOL), and life satisfaction following spinal cord injury (SCI). A two-phase randomized sham-controlled clinical trial was performed in which patients received 5 days of tDCS followed ...

Study compared burn size estimations obtained with three-dimensional (3D) computer-aided software to those obtained with standard-of-care methods. Burn units have historically used paper diagrams to estimate percent burn; however, unintentional errors can occur. The use of a computer program that incorporates wound mapping from photographs onto a 3D human ...

Study evaluated the psychometric properties of the 4-dimension (4-D) itch scale, a modified version of the 5-dimension itch scale, in a sample of individuals with severe burn injury and/or burn injuries to hands, face, and/or feet. Four of the five domains of the 5-dimension itch scale (4-D) were administered ...

Study assess the cardiovascular response to submaximal exercise in children nearly 1 year after burn injury. It was hypothesized that burn injury would lower cardiac output (Q) and stroke volume (SV) during submaximal exercise in burned children compared with non-burned healthy children matched for age and aerobic capacity. Five children ...

Study evaluated the safety of nebulized epinephrine when used as a therapy for smoke inhalation injury in severely burned children. Sixteen patients, 7 to 19 years of age, with burns covering more than 30 percent of the total body surface area, and smoke inhalation injury as diagnosed by bronchoscopy at ...

Study investigated the effect of electrical burns on metabolic rate, body composition, and aerobic capacity in children with electrical burns. Twenty-four severely burned children were studied: 12 children had a combination of electrical and flame burns and 12 matched controls had only flame burns. Exercise assessments were conducted after ...

This review article describes the contributions of the Galveston P50 Research Center in Peri-Operative Sciences (RCIPS) that have changed post-burn care and have considerably reduced post-burn mortality. Since the inception of the P50 RCIPS funding mechanism, the National Institute for General Medical Sciences has supported a team approach to science. ...

Study investigated whether intensive physical exercise (IPE) decreases the frequency of burn scar contracture-releasing procedures in upper-extremity joints in children with extensive burns. The surgical records of 184 children who had undergone axilla, elbow, and/or wrist contracture-releasing procedures were reviewed. All children were 7 years or older and had sustained ...

Study examined the prevalence and impact of cognitive-communication disorders among 144 adults with burn injuries admitted to an inpatient rehabilitation facility. Descriptive statistics were used to identify the prevalence of cognitive-communication deficits on admission and discharge. Two main outcomes were analyzed: (1) cognitive-communication ratings on discharge from inpatient rehabilitation ...

Study evaluated the measurement properties of the Satisfaction With Life Scale (SWLS), developed to quantify global quality of life and satisfaction. SWLS data were obtained from 17,897 individuals enrolled in the Model Systems funded by the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR). They included 8,566 people ...

This literature review summarizes the data supporting the prevalent role that β-adrenergic receptors play in mediating post-burn cardiac dysfunction and the idea that pharmacological modulation of this receptor family is a viable therapeutic target for resolving burn-induced cardiac deficits. Severe burn profoundly affects organs both proximal and distal to ...

Study assessed the effects of gene expression or intracellular signaling in paralyzed muscles of men with long-standing spinal cord injury (SCI). Specifically, it examined the expression of genes (TNFαR, TNFα, IL-6R, IL-6, TWEAK, TWEAK R, atrogin-1, and MuRF1) and abundance of intracellular signaling proteins (TWEAK, TWEAK R, NF-κB, and p-p65/p-50/105) ...

Study compared long-term functional outcome between severely burned children who either participated or did not participate in a 12-week exercise program. A total of 125 severely burned children (mean age 12 years) who received no long-term anabolic drugs chose between a voluntary exercise program (EX-group) and no exercise (NoEX-group) ...

Study examined skeletal muscle mitochondrial respiratory capacity and function in healthy individuals and in burn victims for up to 2 years postinjury. Muscle biopsies were collected from 16 healthy men and from 69 children with burns encompassing at least 30 percent of their total body surface area. Seventy-nine biopsies ...

This systematic review of the literature was conducted to identify evidence to support the use of measures of depression for adults with burn injuries. The goal was to determine the most reliable, valid, and efficient means of identifying adults with symptoms of depression including major depressive disorder. Established guidelines ...

Study examines the incidence and severity of contractures in a large, multicenter, pediatric burn population and determined the associated risk factors for the development of contractures. Data from the National Institute on Disability and Rehabilitation Research Burn Model System database, for pediatric (younger than 18 years) burn survivors from ...

Study investigated whether the administration of oxandrolone, a synthetic testosterone derivative, will improve pulmonary function in burned pediatric subjects. Lung volumes and spirometry were assessed in 54 burned subjects during scheduled outpatient clinic visits 6 months post burn. The subjects were previously randomized to either the control arm or ...

Study compared cardiac output (CO) measurements performed in severely burned children using the transpulmonary thermodilution (TPTD) with the PiCCO (Pulse index Continuous Cardiac Output) system or transthoracic echocardiography (TTE). Fifty-four severely burned children were studied. Outcomes were compared using t-tests, multiple linear regression, and a Bland-Altman plot. An analysis ...

Study investigated the effect of Clostridium difficile-associated diarrhea (CDAD) on morbidity and mortality in severely burned children and identified CDAD risk factors. After retrospective review of 2,840 records, 288 pediatric burn patients were identified as having diarrhea, defined as stool output of more than 10 milliliters per kilogram per ...

Article reviews the current understanding of the pathophysiology of smoke inhalation injury, the best evidence-based treatments, and challenges and future directions in diagnostics and management. Smoke inhalation injury is a serious medical problem that increases morbidity and mortality after severe burns. Despite recent advances in critical care and the ...