Burn Publications

Study compared the rehabilitation outcomes of burn patients admitted to an inpatient rehabilitation facility (IRF) who were discharged to acute care and then readmitted to an IRF (repeaters) with those of burn patients admitted to an IRF only 1 time (nonrepeaters). A secondary analysis was performed of data from the ...

Heterotopic ossification (HO) is the pathologic development of ectopic bone in soft tissues because of a local or systemic inflammatory insult, such as burn injury or trauma. In HO, mesenchymal stem cells (MSCs) are inappropriately activated to undergo osteogenic differentiation. Through the correlation of in vitro assays and in ...

Study investigated whether systemic glucose levels over 150 milligrams per deciliter (mg/dl) in severely burned pediatric patients lead to an overwhelming growth of bacteria in the bronchopulmonary system, subsequently resulting in an increased risk of pulmonary infections. One-hundred six severely burned pediatric patients were enrolled in the study. Patients ...

Article briefly reviews some studies that have used the Uniform Data System for Medical Rehabilitation (UDSMR) to develop a better understanding of burn rehabilitation outcomes. The UDSMR maintains the largest inpatient rehabilitation database in the world, which includes information on approximately 80 percent of all inpatient rehabilitation facilities nationally. ...

Study identified factors associated with chronic pain among survivors of The Station nightclub fire, including those with and without burn injury. The primary outcome measure was the presence and severity of pain. Univariate and stepwise multiple regression analyses were used to examine relationships among variables. Variables considered included age, ...

Study investigated whether patients with burn injury have differences in their cognition compared with other inpatient rehabilitation populations. Data were obtained from the Uniform Data System for Medical Rehabilitation from 2002 through 2011. A total of 5,347 rehabilitation patients with burn injury were compared with 668,816 patients from the ...

Study examined the effects of early outpatient exercise on muscle mass, function, and fractional synthetic rate in severely burned children. Forty-seven children with burns covering at least 40 percent of their total body surface area performed 12-weeks standard of care rehabilitation (SOC) or rehabilitative exercise training (RET) immediately following hospital ...

Study examined the prevalence of hypoglycemia after burn injury and investigated whether hypoglycemia is associated with increased post-burn morbidity and mortality. The analysis included 760 pediatric burn patients, who were stratified according the number of hypoglycemic episodes (blood glucose less than 60 milligrams per deciliter) they experienced while in ...

Study examined the impact of insulin control on outcomes in 243 pediatric patients with massive burns covering 30 percent or more of their total body surface area. Participants were randomized into 2 groups: (1) 145 patients receiving sliding scale insulin to lower blood glucose levels to

Study examined the effect of inhalation injury on burn-induced resting energy expenditure (REE) measurements in children with severe burns. REE, as measured by indirect calorimetry, was used to determine the metabolism levels of patients and to guide their nutrition. Eighty-six children (1–18 years) with 40 percent or more of ...

Study investigated self-reported postburn pruritus (itching) in two groups of adult burn survivors. Descriptive statistics, general linear regression, and mixed model repeated measures analyses were used to test statistical significance. Group 1 consisted of 637 participants who were injured from 2006 to 2010 and were followed up prospectively for ...

BACKGROUND:Oxandrolone, an anabolic agent, has been administered for 1 year post burn with beneficial effects in pediatric patients. However, the long-lasting effects of this treatment have not been studied. This single-center prospective trial determined the long-term effects of 1 year of oxandrolone administration in severely burned children; assessments were continued ...

HYPOTHESIS: Obesity in?uences metabolism and increases the incidence of clinical complications and worsens outcomes in pediatric burn patients. DESIGN: Retrospective, single-center study. SUBJECTS: In all, 592 severely burned pediatric patients who had burns covering more than 30% of the total body surface area and who were treated between 2001 ...

BACKGROUND: Patient survival after severe burn injury is largely determined by burn size. Modern developments in burn care have greatly improved survival and outcomes. However, no large analysis of outcomes in paediatric burn patients with present treatment regimens exists. This study was designed to identify the burn size associated ...

BACKGROUND: Burn induces a hypermetabolic state characterized by alterations in protein metabolism, which is associated with increased morbidity and mortality. Eukaryotic elongation factor 2 (eEF2) plays a crucial role in regulating protein synthesis in many diseases, but whether it participates in burn-induced hypermetabolism is unclear. The aim of this ...

Fenofibrate is a peroxisome proliferator activated receptor alpha agonist that contains both pro and anti-inflammatory properties, and has been used in the treatment of dyslipidemia and diabetes for decades. Its receptors are expressed in the liver, skeletal muscle, cardiac, enteric, and renal cells, which allow it to provide systemic ...