The Mayo Clinic was designated a Traumatic Brain Injury Model System (TBIMS) by the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR) in 1998, and is one of 16 current TBI Model Systems. The Mayo Clinic is designated to provide services along the continuum of care after traumatic brain injury, including: social integration; health and function; and, employment and independent living of individuals of all ages with disabilities related to TBI. Our research program is directly aligned with the NIDILRR mission of improving the lives of individuals who experience TBI, their families, and communities.

Research Projects

As Lead Center

As Participating Center

Title Project Type Start Date End Date
Associations of Early Life Adversity and Neighborhood Environment with TBI Outcomes in the TBIMS National Database Modular (Joint) 10/01/2022 09/30/2027
State Programs and Outcomes from TBI Modular (Joint) 09/01/2022 08/31/2027
Predicting Outcome after Moderate-Severe TBI using a CT Head Deep Learning Model Modular (Joint) 09/01/2022 08/31/2027
BeHealthy: Chronic Disease Management for TBI Collaborative 09/01/2021 08/30/2025
Characterization and Treatment of Chronic Pain after Moderate to Severe Traumatic Brain Injury Collaborative 10/01/2018 09/30/2023
Trajectories of Cognitive Functioning Years after TBI (BTACT) Modular (Joint) 10/01/2017 09/30/2022
Caregiver Resilience: A Longitudinal Investigation Modular (Joint) 09/30/2017 10/01/2022
Return To Driving After Moderate-Severe TBI: Who, When, Where, And How Safe? Modular (Joint) 09/30/2017 10/01/2022
Accelr8: Physical Activity and TBI Modular (Joint) 09/30/2017 10/01/2022
Natural History of Headache - 5-Year Follow-Up Collaborative 09/30/2012 10/01/2017
Mayo Clinic Traumatic Brain Injury Model System
Anne Moessner, MSN, APRN

Department of Physical Medicine and Rehabilitation 200 1st Street SW 1, Rochester,


Mayo Clinic Traumatic Brain Injury Model System

Research Center Staff

Allen W. Brown, M.D.

Principal Investigator/Project Director

Dmitry Esterov, DO

Medical Director/Co-Investigator

Thomas Bergquist, Ph.D., L.P.


Anne Moessner, MSN, APRN

Research Coordinator