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The objective of this module project is to characterize patterns of cognitive function over time among individuals who are 5 years post-TBI. Our work will be organized around the following specific aims:

Aim 1. Characterize patterns of change and stability in cognitive functioning from 5 to 7 years after injury among TBIMS participants.

Aim 2. Identify whether participant and injury factors (age, injury severity, functional status, comorbidities, etc. collected at earlier assessments) are associated with patterns of change in cognitive functioning.

Aim 3: Explore whether rates of decline differ across cognitive domains 5-7 years post-TBI.

This project will employ a longitudinal repeated measures cohort design. We propose to administer the BTACT at the standard TBIMS Year 5 follow-up, and re-evaluate module participants at 2 additional time points spaced about one year apart (i.e., Years 6 and 7 post-injury). This design leverages existing TBIMS information in that participants’ acute injuries and functional status are well documented with core TBIMS NDB measures; these will be included as predictor variables and covariates in our longitudinal analyses.

These data will allow the TBIMS, for the first time, to contribute to the advancement of knowledge regarding the chronic effects of TBI on cognitive functioning.