Search

This study, led by the University of Washington TBI Model System, aims to improve our understanding how well Brite White Light (BWL) therapy works for treating sleep disruption in people who have experienced a traumatic brain injury and are on an acute inpatient rehabilitation unit setting. Participants are assessed ...

This qualitative study uses an in-depth phone interview with the next of kin to learn more about the final year of life for participants in our TBI Model System study that have passed away. Death certificates can often be vague or lacking in the information reported about the primary ...

The goal of our site-specific project is to improve assessment of outcomes across all post-acute settings by evaluating activity limitations and changes in functional activity domains throughout the course of recovery and rehabilitation. Objectives are to: (1) evaluate the sensitivity of Activity Measure for Post-Acute Care (AM-PAC) to longitudinal ...

An exploratory and discovery stage of research, this study looks to assess TBI-induced increases in autonomic dysregulation, metabolic dysfunction, and hyper-inflammation that are associated with earlier time post-injury and reduced cognitive and executive functioning, emotional regulation, and community participation. The study aims to characterize longitudinal changes in physiological markers ...

In light of the high incidence of diagnostic error among patients with disorders of consciousness (DoC) (estimated to be 30-40%), and the risk of premature withdrawal of life-sustaining treatment, the Spaulding-Harvard TBI Model System is testing the validity of an abbreviated version of the Coma Recovery Scale-Revised (CRSR) for ...

The SCI-FI instrument was designed specifically for persons with SCI, regardless of level or severity of injury. The content of the SCI-FI is based upon an extensive review of the literature, input from patients with SCI, and clinician focus groups, and is grounded within the International Classification of Function, Disability, ...

This study is a randomized controlled trial to investigate the efficacy of three approaches (functional task specific practice [FTP] alone, conventional functional electrical stimulation [FES] plus FTP, and wide pulse/high frequency FES plus FTP), to improve upper extremity (UE) function and trunk stability in people with SCI. ...

This is a randomized controlled trial of the effectiveness of a mobile app mood self-monitoring intervention augmented by brief supportive telephone calls to decrease emotional distress in persons with complicated mild to severe TBI at least one year post-injury. The active treatment group will be compared to a wait-list ...

In close collaboration with women from our National Community Advisory Board (NCAB), this study is a randomized controlled trial of our intervention, Zest: Promoting the Psychological Health of Women with SCI. We will enroll a national sample of 192 women with SCI, half of whom will be offering the ...

Our study objective is to compare the effect of intravesical Lactobacillus rhamnosusGG (LGGÒ) mixed with normal saline, to that of a normal saline bladder wash (BW) in the self-management of urine and bladder symptoms. We have utilized an efficient, two-phase design with separate tests of efficacy: in the first ...

Although the physical outcomes associated with SCI have been widely studied, the psychological consequences of sustaining a SCI remain less explored. Prolonged exposure therapy (PE) is a well-researched and highly effective treatment for PTSD across multiple traumas. However, early intervention with Brief PE for PTSD prevention among people post SCI ...

This project will produce new knowledge and information to address current evidence gaps in the management of brain injury as a chronic health condition and, in so doing, will help optimize health, function, and community integration after traumatic brain injury (TBI). The primary output of this project will be ...

CARE4TBI project is a pragmatic, stakeholder-driven observational study which aims to: 1) standardize electronic medical record (EMR) documentation of rehabilitation therapy to allow extraction for research and operations, 2) compare the effectiveness of well-defined rehabilitation approaches to improve community participation and functional independence of patients with TBI, and 3) ...

The Virginia Spinal Cord Injury Model System (VSCIMS) brings together the Virginia Commonwealth University Center for Rehabilitation Science and Engineering (VCU-CERSE), Sheltering Arms Institute, and Central Virginia Veterans Health System with participating Virginia level I trauma centers, community health providers, state government agencies, and SCI consumer groups. Our goal ...

Persons with SCI can develop a wide array of secondary complications post-injury. In particular, cardiometabolic disease (CMD) is a leading cause of death after the first year of injury. However, the risk of developing CMD among individuals with SCI is modifiable and may be mitigated by targeted nutrition intervention. Utilizing ...

Gabapentin is a medication commonly used in SCI to manage neuropathic pain. Emerging preclinical and clinical evidence suggests that early initiation of low to medium doses of gabapentin and continued delivery for a range of 2 weeks to 4 months has a persistent, positive effect on motor and autonomic neurologic ...

Chronic pain after SCI typically begins within the first 6 months post-injury and remains prevalent over time, affecting as many as 80% of individuals at 25 years post-injury. This secondary condition has a profound impact on all arenas of life, has been associated with depression, unemployment, and reduced quality of ...