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This study proposes and tests a conceptual model to explain the role of personal characteristics, injury characteristics, prescribed treatments, environmental support and health behavior factors on bladder and bowel complications and downstream effects on quality of life (QOL) in persons with chronic SCI. The scope of this study builds ...

This study will evaluate the efficacy of a newly developed self-management program, Health Mechanics, to develop and improve bowel and bladder management skills among persons with new SCI. Health Mechanics was designed by the study PI, Dr. Michelle Meade, between 2007 and 2009 with funding from the PVA Educational ...

The primary objectives of this investigation are to 1) compare bone mineral density (BMD) at the hip, distal femur and proximal tibia in subjects receiving a single dose of intravenous ZA to control subjects and 2) observe the timing of metabolic indexes of bone formation and resorption within the ...

Chronic pain, depression and difficulty being physically active are common problems for many people with SCI that have a negative effect on overall quality of life. These problems are also very complex and difficult to treat in the current health care system. Our study aims to improve treatment for ...

Frazier Rehab is recognized as a leader in the field of motor recovery, particularly through the use of locomotor training (LT), an activity-based intervention in which an individual with paralysis is suspended over a treadmill while specially trained therapists move his or her legs to simulate walking. LT has ...

Individuals with spinal cord injury (SCI) are living to ages when metabolic disorders are highly prevalent. The combination of impaired glucose tolerance and insulin resistance can disrupt lipid metabolism and increase the risk of cardiovascular disease and diabetes, and contribute to an accelerated aging process in the SCI population. Feasible ...

Patients with acute spinal cord injury (SCI) frequently develop infections, most commonly pneumonia and urinary tract infections. These infections can effect recovery of function and sometimes lead to death. The autonomic nervous system (ANS) is a part of the nervous system that regulates bodily functions ...

The goal of the Social Interaction Skills Training study is to not only assess the magnitude of social anxiety and social phobia as a result of disfigurement following burn injury, but also to provide and document the efficacy of a social skills training program developed to overcome feelings of ...

The purpose of this study is to quantify the biomechanical effects of a therapist stretching a patient's burn scars. Burn scars are the most common complication of burn injury and can alter the way a person's joints move and lower their quality of life. A common treatment for burn scars ...

This study,also site specific,is a continuation from the previous funding cycle. It focuses on Acute Stress Disorder(ASD) and Posttraumatic Stress Disorder (PTSD), a problem that can impair the well-being of burn patients. The study proposes to determine the causes of ASD and PTSD and the relationship between these two ...

For this project,our objective is to improve rehabilitative outcomes for children with burns >30% total body surface area burned by utilizing an in-house outpatient rehabilitation program, with or without the use of anabolic agents (oxandrolone, Ketoconazole, or propranolol). The supervised exercise program has shown to be effective in ameliorating ...

The objective of this study is to conduct a trial of the efficacy of a formal, 12-week program of aerobic training in promoting return to fitness and improving adherence to an exercise program. Participants’ baseline aerobic capacity will serve as the control for secular trends. Outcome measures will include the ...

Importance: Burns are painful, life threatening and disfiguring. Severe psychological distress, pain and sleep disturbance are among the most common, enduring and disabling of secondary complications, however, no evidence based treatments exists for these complex problems in the acute burn care setting. Design: Randomized, controlled effectiveness trial, interventionist blinded ...

Our broad, long-term objective is to improve outcomes after a burn injury by utilizing an expanded care coordinator (ECC) to assist with the management of barriers to effective burn rehabilitation. Our specific aim is to determine if the ECC intervention will improve outcomes across multiple domains for adults with ...

The broad long-term objective is to understand the cause of hypertrophic scarring after burns, with the intent of eliminating this devastating outcome and thereby improving rehabilitation after burn injury. The specific aim is to translate the porcine gene data to the human equivalent and then identify the gene pathways ...

The LTF-NDS study is a prospective, longitudinal design. The target population of this LTF-NDS clearly relates to the NIDRR priority. The existing BMS database tracks and evaluates individuals through 2 years follow-up. This baseline data includes a comprehensive core BMS-NDSC dataset. The proposed LTF-NDS study will use these prospectively ...

This project is a pilot study investigating the potential benefits of two customized gaming systems (Wii Sports for the Nintendo Wii and Kinects Sports for the Xbox 360) as an adjunctive rehabilitation intervention in burn care. The study explores the mechanism by which gaming technology participation may benefit the ...

During past NIDRR BMS funding cycles, we have focused on identifying patients’ barriers to returning to work. To advance our long-term efforts of facilitating return to work, we will utilize internet technology to establish a web-based dissemination effort to provide education regarding challenges and processes encountered following a significant ...

The Burn National Database indicates a high prevalence of post-burn itch, initially affecting >90% of individuals and persisting for >40% of long-term burn survivors. Feedback from burn survivors at the 2006 State of the Science Conference supports these data. Itching affects quality of life with significant impact on sleep, ...

In concordance with the priority of assessing long-term outcomes, we are positioned to collect data on over 1300 individuals at 5, 10, and 15 years post-burn in the next 5 year-cycle. Based on recent enrollment statistics during the last BMS funding cycle and our annual admission rate of over ...