What is the study about?
Monoamine transporters are protein structures that help regulate the levels of neurotransmitters that send signals to the nerve structure. Dopamine and serotonin are examples of compounds that send signals throughout the body. They are important in regulating a variety of brain activities including memory, executive functioning ...
What is the study about?
The purpose of this study was to assess the association between post-traumatic epilepsy (PTE), occurring during the first 2 years post-injury, and frequency of mental health outcomes (depression and/or anxiety) during that same time period in a group of individuals with moderate-to-severe traumatic brain injury (TBI) ...
What is the study about?
The adapted Marshall computed tomography (CT) classification scheme is used to classify the severity of TBI using the results from a CT scan. The aim of this study was to first examine the predictive relationship between an adapted Marshall classification scheme and other clinical measures of ...
What is the study about?
This study examines the probability of returning to productivty, defined as engagement in school or work, over time up to 5 years following moderate-to-severe traumatic brain injury (TBI).
What did the study find?
This study found several factors associated with the likelihood of returning to work following a ...
What is the study about?
The purpose of this study was to describe the characteristics and concerns of caregivers of adults with traumatic brain injury (TBI) over the first few months after discharge of the TBI survivor into the community.
What did the study find?
This study found that caregivers of TBI survivors ...
Objective: This study compared traumatic brain injury (TBI) outcomes from 2 cohorts: the National Institute on Disability, Independent Living, and Rehabilitation Research Traumatic Brain Injury Model Systems (TBIMS) in the United States and Longitudinal Head Injury Outcome Study conducted in Victoria, Australia, by the Monash Epworth Rehabilitation Research Centre (MERRC).
Design: ...
Importance: Traumatic brain injury (TBI) leads to 2.9 million visits to US emergency departments annually and frequently involves a disorder of consciousness (DOC). Early treatment, including withdrawal of life-sustaining therapies and rehabilitation, is often predicated on the assumed worse outcome of disrupted consciousness.
Objective: To quantify the loss of consciousness, factors ...
What is spasticity?
Spasticity is the uncontrolled overactivity of muscles caused by disrupted signals from the brain. It is common in persons with more severe traumatic brain injuries (TBIs). People with spasticity may feel as if their muscles have tightened and will not relax or stretch. They may also feel muscle ...
What is the study about?
The goal of this case series report was to look for improvement in bowel and bladder continence and cognition in patients with severe traumatic brain injury (STBI). The functional independence measure (FIM) was used to evaluate study participants at discharge from inpatient rehabilitation (IR). Researchers were ...
What is the study about?
This study was conducted to evaluate the usefulness of the Glasgow Coma Scale (GCS) in accounting for differences in life outcomes after injury. Traditionally, the GCS is used to predict survival in a hospitalized patient population rather than as a functional outcome. The GCS scale has ...
What is the study about?
There are three main indicators of severity of traumatic brain injury (TBI). These indices are length of coma, posttraumatic amnesia (PTA), and the degree of disturbance of consciousness soon after injury (Glasgow Coma Scale score). Researchers may sometimes rely on self-reported TBI severity. The goal of ...
What is the study about?
Neuroprotective treatments have shown promise in improving recovery from traumatic brain injury (TBI) in animals. However, no studies to date have shown such treatments to be effective in humans. One reason for this may be because such treatments are given to animals before or soon after ...
What is the study about?
This study uses the Traumatic Brain Injury Model Systems national database to examine the prevalence of obesity in individuals 1 to 25 years following traumatic brain injury (TBI).
What did the study find?
The study found that rates of obesity and overweight problems increased overtime after TBI, with ...
Background: Early detection of consciousness after severe brain injury is critical for establishing an accurate prognosis and planning appropriate treatment.
Objectives: To determine which behavioural signs of consciousness emerge first and to estimate the time course to recovery of consciousness in patients with severe acquired brain injury.
Methods: Retrospective observational study using ...
In response to the need to better define the natural history of emerging consciousness after traumatic brain injury and to better describe the characteristics of the condition commonly labeled posttraumatic amnesia, a case definition and diagnostic criteria for the posttraumatic confusional state (PTCS) were developed. This project was completed by ...
The Model Systems Knowledge Translation Center presents an audio factsheet on Vegetative And Minimally Conscious States After Severe Brain Injury. The factsheet was developed by Sherer M, Vaccaro M, Whyte J, Giacino JT, & the Consciousness Consortium in collaboration with the Model Systems Knowledge Translation Center.The information in this factsheet ...
Learn about vegetative and minimally conscious states after severe traumatic brain injury. This factsheet explains changes in consciousness after severe TBI.
What is the study about?
This project aims to develop a case definition and diagnostic criteria for post-traumatic confusional state (PTCS) following traumatic brain injury (TBI). The study describes clinical findings that establish a diagnosis of PTCS. Second, the study presents criteria for describing recovery from severe states of altered consciousness, ...
What is a concussion?
A concussion is a mild traumatic brain injury (TBI) caused by a blow to the head which causes the head and brain to move rapidly back and forth. This can happen due to a car or bike crash, a fall, an assault, or a sports injury. In ...