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Study assesses the association between heterotopic ossification (HO) and upper-extremity contracture by comparing goniometric-measured active range of motion (ROM) outcomes of burn patients with and without HO. Data were obtained from the Burn Model System National Database for all patients more than 18 years of age with elbow contracture at ...

Study compared Mepilex Ag, a silver-impregnated foam dressing, and Suprathel, a polylactic acid membrane, in the outpatient treatment of partial-thickness burns in pediatric and adult patients. Patients were enrolled in a randomized, controlled, prospective clinical trial. Time to reepithelialization, wound pain, discomfort during dressing changes, and treatment cost were monitored. ...

Study reviews the neural circuitry involved in post-burn symptoms and provides a scientific rationale for specific non-invasive brain stimulation (NIBS) targets that can potentially treat these conditions. Burn survivors experience myriad associated symptoms such as pain, pruritus, fatigue, impaired motor strength, post-traumatic stress, depression, anxiety, and sleep disturbance. Many of ...

Study tested the hypothesis that intravenously administered adipose-derived stem cells (ASCs) effectively ameliorate the severity of pulmonary microvascular hyper-permeability in ovine models of acute respiratory distress syndrome (ARDS) induced by smoke inhalation. Ten female sheep were surgically prepared. ARDS was induced by cooled cotton smoke inhalation. Following injury, sheep were ...

Study assessed the association between head and neck (H&N) burn status and long-term outcomes for life satisfaction, body image satisfaction, community integration, and health-related quality of life among adolescent burn survivors. Data collected from the Burn Model System National Database (2006-2015) for 392 burn survivors between 14 and 17.9 years ...

Study examined agreement between pediatric burn survivor self- and caregiver proxy-report on multiple Patient Reported Outcomes Measurement Information System (PROMIS) domains and identified factors associated with differences between self- and proxy-reports. Two hundred seventy-four children and their caregivers completed PROMIS measures (physical function, depression, peer relationships, pain interference, and anger) ...

Study examined the physical and mental health, satisfaction with life, and community integration of burn survivors up to 20 years after injury. Data were obtained from the Burn Model System National Longitudinal Database (1993-2020). Patient-reported outcome measures were collected at discharge (preinjury status recall) and 5 years, 10 years, 15 ...

The ability to improve disaster response preparedness and processes relies heavily on the highly practical and necessary but flawed concept of “lessons learned”. However, in order to further evaluate preparedness, improve processes for response and properly allocate resources for rehabilitation and recovery after disasters, patient-centric longitudinal assessment measures are needed. ...

Burn injury detrimentally affects the myocardium, primarily due to over-activation of β-adrenergic receptors (β-AR). Autopsy reports reveal that patients often suffer from right ventricle (RV) failure. Since burn injury affects β-AR signaling in the left ventricle (LV), the authors proposed that β-AR signaling may also be altered in the RV. ...

Study evaluated the degree of body composition changes in different anatomical regions during hospitalization in the intensive care unit (ICU). Twenty-four severely burned children admitted to the ICU underwent a dual-energy x-ray absorptiometry within 2 weeks after injury and 2 weeks before discharge to determine body composition changes. All patients ...

Study was conducted to build bridges across the self-reported adolescent (ages 11 to 18 years) and young adult (ages 19 to 30 years) versions of the Shriners Hospitals for Children/American Burn Association Burn Outcomes Questionnaires (BOQs). Data were available on 353 unique adolescents and 148 young adults from the Multi-Center ...

Study compared exercise capacity and body composition in adult men and boys before and after a rehabilitative exercise program (RET). Forty boys (aged 7 to 17 years,) were matched to 35 adult men (aged 18 to 45 years) based on extent of burn injury (total body surface area burned: boys ...

Study assessed whether the Burn Model System (BMS) National Database, one of the largest prospective, longitudinal, multi-center research repositories collecting patient-reported outcomes after burn injury, is representative of the population that is eligible to participate. Eligibility for the database is based on burn size and receipt of autografting surgery. Data ...

Study analyzed qualitative data collected using the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey at one burn center over two years to identify areas for care improvement. Comments returned with survey may provide important patient perspectives. A total of 610 inpatient HCAHPS surveys (21 percent response rate) ...

Study investigated the acute effect of severe burn trauma on liver mitochondrial respiratory capacity and coupling control as well as the signaling events underlying these alterations. Male BALB/c mice (8–12 weeks) received full-thickness scald burns on approximately 30 percent of the body surface. Liver tissue was harvested 24 hours post ...

Study examined the existing literature on burns to see if the differences between pediatric and adult calcemic and parathyroid hormone (PTH) responses to burn injury. The authors’ research has shown that children present with sustained hypocalcemia, hypomagnesemia, and hypoparathyroidism consistent with up-regulation of the parathyroid calcium-sensing receptor (CaSR) while adults ...

Study compared the cardiovascular effects of an exercise program incorporating a large number of interval training sessions with a traditional exercise program incorporating a small number of interval training sessions in severely burned children. Forty patients who completed a large number of sessions (at least three sessions per week) were ...

Study investigated which cells within the adipose tissue contributed toward the production of inflammatory mediators and whether adipose-derived stem cells (ASCs) are affected by the post-burn inflammatory environment. Using a 60-percent rat scald burn model, the authors conducted a series of experiments to determine which cells isolated from the adipose ...

Study assess the cardiovascular response to submaximal exercise in children nearly 1 year after burn injury. It was hypothesized that burn injury would lower cardiac output (Q) and stroke volume (SV) during submaximal exercise in burned children compared with non-burned healthy children matched for age and aerobic capacity. Five children ...