What is the study about?
This study evaluated whether tumor necrosis factor (TNF)-α is associated with disinhibition and thoughts of suicide 6 and 12 months after traumatic brain injury (TBI). TNF-α is one of the inflammatory cytokines produced early after TBI. TNF-α is associated with thoughts of suicide in the general ...
What is the study about?
The most common complication after a traumatic brain injury (TBI) is post-traumatic depression (PTD). This study looked at whether inflammation profiles from the acute phase of TBI can predict risk for PTD 6 and 12 months after the injury. People with TBI may have better outcomes ...
What is a concussion?
A concussion is a mild traumatic brain injury (TBI) caused by a blow to the head which causes the head and brain to move rapidly back and forth. This can happen due to a car or bike crash, a fall, an assault, or a sports injury. In ...
What is the study about?
The study explored the problem solving treatment (PST) for service members with traumatic brain injury (TBI). The study tested the effectiveness of the treatment in reducing concussive symptoms. PST is a telephone-based treatment, also known as telehealth.
What did the study find?
Researchers propose that the telephone-based PST ...
What is acute inpatient rehabilitation?
Acute inpatient rehabilitation (rehab) is an intensive form of medical rehabilitation in which patients receive three or more hours per day of core therapies (physical therapy, occupational therapy and speech therapy) overseen by a physician specialized in rehabilitation with around the clock nursing care. This team ...
Abstract
Dopaminergic (DA) system function is frequently disrupted after traumatic brain injury (TBI). However, published interventions that target the DA system with the hope of enhancing functional outcomes are inconclusive, partially because of the lack of DA signaling biomarkers that can be used to select patients likely to benefit from DA-directed ...
Introduction: Understanding the impact of disease on function and improving functional outcomes is an important goal of rehabilitation. This scoping review analyzes 25 years of published traumatic brain injury (TBI) clinical rehabilitation research (CRR) to determine the frequency with which function is a research goal.
Methods: The review protocol was prepared ...
What is the study about?
Traumatic brain injury (TBI) may impact one’s self-awareness of emotional and behavioral functioning. This study looked at how changes in self-awareness and depression affect what people with TBI report about their memory, health-related qualityof-life (QoL), and satisfaction with life.
What did the study find?
The investigators reported their ...
Objective: To describe trajectories of functioning up to 5 years after traumatic brain injury (TBI) that required inpatient rehabilitation in the United States using individual growth curve models conditioned on factors associated with variability in functioning and independence over time.
Design: Secondary analysis of population-weighted data from a multicenter longitudinal cohort ...
What is the study about?
It is often difficult to convey to stakeholders of clinical research whether something being reported is clinically meaningful. One measure of increased interest and importance is the minimally clinically important difference (MCID) and is discussed in this article. The MCID is defined as the smallest improvement ...
What is the study about?
This study compares the characteristics of individuals with TBI who die from unintentional poisoning to those of individuals with TBI who die from other causes to see what characteristics, if any, distinguish the two groups. In doing so, the study aims to better understand the risks ...
What is the study about?
This study uses the Traumatic Brain Injury Model Systems national database to examine the prevalence of obesity in individuals 1 to 25 years following traumatic brain injury (TBI).
What did the study find?
The study found that rates of obesity and overweight problems increased overtime after TBI, with ...
What is the study about?
Neuroprotective treatments have shown promise in improving recovery from traumatic brain injury (TBI) in animals. However, no studies to date have shown such treatments to be effective in humans. One reason for this may be because such treatments are given to animals before or soon after ...
What is the study about?
There is a critical need to generate traumatic brain injury clinical practice guidelines. The aim of this study was to form a multidisciplinary group of clinicians and researchers to identify and evaluate evidence-based best practices for patients with TBI undergoing rehabilitation and describe the process for ...
What is the study about?
The adapted Marshall computed tomography (CT) classification scheme is used to classify the severity of TBI using the results from a CT scan. The aim of this study was to first examine the predictive relationship between an adapted Marshall classification scheme and other clinical measures of ...
What is the study about?
Traumatic brain injury (TBI) survivors are typically classified by injury severity using a measure that relies heavily on level of consciousness. The most common measure is the Glasgow Coma Scale (GCS) and is very helpful in planning early treatment. It is often used to establish prognosis, ...
What is the study about?
This study aims to address the gap in treatments for psychological distress (feeling sad, afraid, anxious, depressed, etc.) in persons with traumatic brain injury (TBI). This study examined Acceptance and Commitment Therapy (ACT). ACT is focused on helping people to accept whatever they are thinking or ...
This is a part of the Hot Topic podcast series from the Model Systems Knowledge Translation Center on TBI and Depression. Dr. Samantha Artherholt discusses Why It's Critical to Treat Depression in People with TBI.
I think there’s so much that goes into that in terms of depression after brain injury. ...