Burn Publications

Study examined the prevalence of hypoglycemia after burn injury and investigated whether hypoglycemia is associated with increased post-burn morbidity and mortality. The analysis included 760 pediatric burn patients, who were stratified according the number of hypoglycemic episodes (blood glucose less than 60 milligrams per deciliter) they experienced while in ...

Study identified factors associated with long-term insulin resistance in pediatric burn injury survivors. The study sample consisted of 61 pediatric burn injury survivors 24 to 36 months after the burn injury, who underwent an oral glucose tolerance test. To assess insulin resistance, the authors calculated the area under the ...

Study examined the impact of insulin control on outcomes in 243 pediatric patients with massive burns covering 30 percent or more of their total body surface area. Participants were randomized into 2 groups: (1) 145 patients receiving sliding scale insulin to lower blood glucose levels to

Study investigated whether systemic glucose levels over 150 milligrams per deciliter (mg/dl) in severely burned pediatric patients lead to an overwhelming growth of bacteria in the bronchopulmonary system, subsequently resulting in an increased risk of pulmonary infections. One-hundred six severely burned pediatric patients were enrolled in the study. Patients ...

Article briefly reviews some studies that have used the Uniform Data System for Medical Rehabilitation (UDSMR) to develop a better understanding of burn rehabilitation outcomes. The UDSMR maintains the largest inpatient rehabilitation database in the world, which includes information on approximately 80 percent of all inpatient rehabilitation facilities nationally. ...

Study identified factors associated with chronic pain among survivors of The Station nightclub fire, including those with and without burn injury. The primary outcome measure was the presence and severity of pain. Univariate and stepwise multiple regression analyses were used to examine relationships among variables. Variables considered included age, ...

Study examined the relationship between long-term functional recovery and total body surface area (TBSA) burned. Data were analyzed for 147 burned subjects who completed the Young Adult Burn Outcome Questionnaire at initial baseline contact, 2 weeks, and at 6 and 12 months after initial questionnaire administration. One hundred twelve ...

Study compared the rehabilitation outcomes of burn patients admitted to an inpatient rehabilitation facility (IRF) who were discharged to acute care and then readmitted to an IRF (repeaters) with those of burn patients admitted to an IRF only 1 time (nonrepeaters). A secondary analysis was performed of data from ...

Study explored whether trajectories of common biomedical markers of metabolism and inflammation can be utilized to determine survival in pediatric burn patients. A total of 230 severely burned children with burns exceeding 30 percent of their total body surface, requiring at least 1 surgical procedure were enrolled in this ...

Study investigated self-reported postburn pruritus (itching) in two groups of adult burn survivors. Descriptive statistics, general linear regression, and mixed model repeated measures analyses were used to test statistical significance. Group 1 consisted of 637 participants who were injured from 2006 to 2010 and were followed up prospectively for ...

BACKGROUND: Burn induces a hypermetabolic state characterized by alterations in protein metabolism, which is associated with increased morbidity and mortality. Eukaryotic elongation factor 2 (eEF2) plays a crucial role in regulating protein synthesis in many diseases, but whether it participates in burn-induced hypermetabolism is unclear. The aim of this ...

Fenofibrate is a peroxisome proliferator activated receptor alpha agonist that contains both pro and anti-inflammatory properties, and has been used in the treatment of dyslipidemia and diabetes for decades. Its receptors are expressed in the liver, skeletal muscle, cardiac, enteric, and renal cells, which allow it to provide systemic ...

BACKGROUND: Patient survival after severe burn injury is largely determined by burn size. Modern developments in burn care have greatly improved survival and outcomes. However, no large analysis of outcomes in paediatric burn patients with present treatment regimens exists. This study was designed to identify the burn size associated ...

HYPOTHESIS: Obesity in?uences metabolism and increases the incidence of clinical complications and worsens outcomes in pediatric burn patients. DESIGN: Retrospective, single-center study. SUBJECTS: In all, 592 severely burned pediatric patients who had burns covering more than 30% of the total body surface area and who were treated between 2001 ...

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BACKGROUND:Oxandrolone, an anabolic agent, has been administered for 1 year post burn with beneficial effects in pediatric patients. However, the long-lasting effects of this treatment have not been studied. This single-center prospective trial determined the long-term effects of 1 year of oxandrolone administration in severely burned children; assessments were ...

Objective: Life experience shapes personality and chronic trauma in childhood has been associated with risk for development of subsequent personality disorder. The purpose of this study is to determine the prevalence and character of personality disorders and traits in young adult survivors of severe pediatric burn injury. Method: SCID-II ...

Objective: To determine the safety and efficacy of propranolol given for 1 year on cardiac function, resting energy expenditure, and body composition in a prospective, randomized, single-center, controlled study in pediatric patients with large burns. Background: Severe burns trigger a hypermetabolic response that persists for up to 2 years ...

The objective of the study is to evaluate the validity and reliability of the Itch Man Scale developed in 2000 by Blakeney and Marvin in assessing the intensity of itch in the pediatric burn patient. Forty-five patients (31 males and 14 females; average age 9.9 ± 5.0 years; and ...

Article reviews changes in burn care at the Harborview Burn Center in Seattle, WA, from 1974 to 2009. It reports results and include observations on changes in numbers of standard and short-stay admissions, age distribution, transport patterns, percent of total body surface area burned, race/ethnicity, payer status, fluid creep, ...