Burn Publications

Study investigated whether the administration of oxandrolone, a synthetic testosterone derivative, will improve pulmonary function in burned pediatric subjects. Lung volumes and spirometry were assessed in 54 burned subjects during scheduled outpatient clinic visits 6 months post burn. The subjects were previously randomized to either the control arm or ...

Study examined skeletal muscle mitochondrial respiratory capacity and function in healthy individuals and in burn victims for up to 2 years postinjury. Muscle biopsies were collected from 16 healthy men and from 69 children with burns encompassing at least 30 percent of their total body surface area. Seventy-nine biopsies ...

Study investigated the effect of Clostridium difficile-associated diarrhea (CDAD) on morbidity and mortality in severely burned children and identified CDAD risk factors. After retrospective review of 2,840 records, 288 pediatric burn patients were identified as having diarrhea, defined as stool output of more than 10 milliliters per kilogram per ...

Article provides a brief overview of the purpose of and information included in the Burn Injury Model System (BMS) National Database. The BMS collects informative data on both adult and pediatric survivors following a major burn. It also collects information on return to work, school, and participation in the ...

Study investigated whether administration of oxandrolone for 2 years yields greater effects on bone mineral content (BMC), bone mineral density (BMD), and growth in 119 hospitalized children with severe burn injury (30 percent or more total body surface area burned). Eighty four patients were randomized to the control group, ...

Study examines the incidence and severity of contractures in a large, multicenter, pediatric burn population and determined the associated risk factors for the development of contractures. Data from the National Institute on Disability and Rehabilitation Research Burn Model System database, for pediatric (younger than 18 years) burn survivors from ...

Study determined the temporal relationship between burn trauma and mitochondrial function in murine skeletal muscle local to and distal from burn wounds. Male mice (8-10 weeks old) were burned by submersion of the dorsum in water to create a full thickness burn on approximately 30 percent of the body. ...

Article reviews the data pertaining to the effects of pharmacological interventions on muscle protein synthesis, breakdown, and net balance (synthesis minus breakdown) in severely burned patients. A review of the literature related to skeletal muscle protein metabolism following burn injury was conducted. Emphasis was on studies utilizing stable isotope ...

Study evaluated the efficacy of utilizing an expanded care coordinator (ECC) to supplement existing outpatient burn rehabilitation services. In this between-group, single-blind, randomized controlled trial, the 41 patients in the control group received standard outpatient care and the 40 experimental group patients received additional services provided by the ECC, ...

Study examined the prevalence of posttraumatic stress disorder (PTSD) in pediatric burn survivors who had been treated for acute stress disorder symptoms during their initial hospitalization and compared them to patients who had been asymptomatic for acute stress disorder. Participants were primarily matched on total body surface area burned ...

Study assessed the psychometric properties of the full-version Community Integration Questionnaire (CIQ-15) in the adult burn population. Data were obtained from a multicenter longitudinal data set of 492 burn survivors. The questionnaire items were evaluated for clinical and substantive relevance; validation procedures were conducted on different samples of the ...

Study investigated whether the Vancouver Scar Scale (VSS) can be used to define hypertrophic scarring (HTS) in an objective, reliable manner. An online survey sent to 1,000 burn care providers asked respondents what VSS score indicates HTS and asked them to score scar photos using the VSS. Receiver operating ...

Study identified and analyzed clinical factors that predict heterotopic ossification (HO), the ectopic formation of lamellar bone, in adults with burn injuries. Data were collected from six high-volume burn centers in the Burn Injury Model Systems (BMS) database. The BMS, funded by the National Institute on Disability, Independent Living ...

Study examined long-term psychological distress and quality of life (QOL) in young adult survivors of pediatric burns using the World Health Organization Disability Assessment Scale II (WHODAS) and the Burn Specific Health Scale-Brief (BSHS-B). The WHODAS measures health and disability and the BSHS-B measures psychosocial and physical difficulties. Fifty ...

Study examined the long-term quality of life (QOL) of pediatric burn survivors with and without inhalation injuries. It was hypothesized that patients with inhalation injury would report more disability and lower QOL. Participants included 51 patients with inhalation injury and 72 without inhalat ion injury who had burns ...

Study investigated whether wound healing and perioperative hemodynamics are affected by propranolol administration in severely burned adults. Sixty-nine adult patients with burns covering at least 30 percent of their total body surface area received standard burn care, 35 patients with and 34 without (controls) propranolol. Propranolol was administered within ...

Study analyzed the variation in rehabilitation utilization by state of hospitalization for patients hospitalized with burn injury. This retrospective cohort study used nationally collected data over a 10-year period (2001 to 2010), from the Healthcare Cost and Utilization Project State Inpatient Databases. A total of 57,968 patients hospitalized for ...

This 5-year prospective multicenter study included 152 adults with burn injuries, ages 19 to 30 years, who completed the Young Adult Burn Outcome Questionnaire (YABOQ) up to 36 months after injury. The YABOQ measures 15 patient-reported outcomes including physical, psychological, and social statuses and symptoms such as itch and ...

Study identified predictors for discharge to independent versus non-independent living status in older patients hospitalized for burns. Patient, injury, and treatment outcomes data were collected from 591 patients aged ≥55 years who were treated and discharged alive from three burn centers participating in the Burn Model Systems project from ...

Study investigated whether expression of interleukin 8 (IL-8), a major mediator for inflammatory responses, can be used to predict post-burn sepsis, infections, and mortality. Plasma cytokines, acute-phase proteins, constitutive proteins, and hormones were analyzed during the first 60 days after injury from 468 pediatric burn patients. Demographics and clinical ...