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Dr. Basil A. Pruitt Jr., a consummate clinical and translational surgeon-scientist, has been spent over half a century at the forefront of an advancing standard of burn care. Commanding the United States Army Institute for Surgical Research in San Antonio, he trained generations of leading burn clinicians and allied scientists. ...

Increased resting metabolic rate and skeletal muscle wasting are hallmarks of the pathophysiological stress response to severe burn trauma. However, whether these two responses occur independently in burn patients or are in fact related remains unclear. In light of recent evidence demonstrating that increased proteolysis in skeletal muscle of ...

This study documented the safe and effective practice of taking propranolol at an age-appropriate dose in pediatric burn patients. Propranolol has shown to be effective in treating the hypermetabolic state secondary to a major burn injury. One hundred four burn-injured children with a 30 to 92 percent total body surface ...

Topical antimicrobials are one component in burn wound care. These agents suppress microbial growth to advantage skin cells and wound healing. Topical antimicrobials can be divided into 2 superclasses: antiseptics and antibiotics. This article reviews the 4 main classes of topical antiseptics (emulsifiers, acids, oxidizers, and heavy metals) and antiseptic-impregnated ...

Study summarized successful use of trajectory curves to inform the development and eventual clinical implementation of Life Impact Burn Recovery Evaluation (LIBRE) Profile trajectory curves for specific domains that focus on social re-integration. Trajectory curves are valuable tools to benchmark patient health status and predict future outcomes. A scoping review ...

Study evaluated the cross-cultural validity of a newly developed Spanish version of the Young Adult Burn Outcome Questionnaire (YABOQ), a validated, English-language patient-reported outcome assessment of young adults’ recovery from burn injury. The 48-item instrument assesses burn outcomes across 15 age-relevant domains of health-related quality of life. Secondary data from ...

As part of a multicenter longitudinal study of patient-reported outcomes, a minimum benchmark for follow-up was set at 80 percent. In review of the Northwest Regional Burn Model System’s participation, it was noted that this benchmark was not consistently met. Thus, a set of actions were identified, termed Best Practices ...

Article describes a study underway that uses digital phenotyping to characterize burn survivors’ psychosocial recovery. Digital phenotyping refers to the process of quantifying individual behavior using data generated through human interaction with electronic devices, in particular smartphones. This data can be both: (1) active, wherein the individual is required to ...

Study examined the validity and reliability of the Patient-Reported Outcomes Measurement Information System (PROMIS)-29 scores among burn survivors. The PROMIS-29 scores of physical function, anxiety, depression, fatigue, sleep disturbance, ability to participate in social roles, and pain interference were evaluated for validity and reliability in adult burn survivors. Unidimensionality, floor ...

Study examined the rate of readmission from inpatient rehabilitation facilities (IRFs) to acute care hospitals (ACHs) during the first 30 days of rehabilitation stay, the variation in 30-day readmission rate across IRFs, and the extent that patient and facility characteristics contribute to this variation. Adult IRF discharges from 944 IRFs ...

Study examined the effect of scald burn injury on rat tracheal epithelium at 5 days after injury and tested the hypothesis that treatment with febuxostat (FBX), an inhibitor of xanthine oxidase (XO), can be protective of cell homeostasis. Sprague Dawley rats were randomly divided into uninjured (sham), injured (control), and ...

Study investigated the relationships between pre-existing migraines and acute (within 72 hours) symptoms and cognitive performance after a suspected concussion. From a total of 39,161 adolescent athletes who underwent baseline preseason testing, 633 were assessed within 3 days of a suspected concussion. Of these, 59 (9.3 percent) reported a history ...

Study described pain intensity and interference at baseline and 1 year post injury in burn, traumatic brain injury (TBI), and spinal cord injury (SCI) survivors compared to each other and with the general population (GP). It also evaluated the feasibility and utility of custom Patient Reported Outcomes Measurement Information System ...

Study investigated whether the “sacral sparing” definition for completeness of traumatic spinal cord injury (SCI) is a more stable definition than the previously used Frankel Classification. A retrospective analysis was conducted of 804 individuals with traumatic SCI who were enrolled in the SCI Model Systems database between 2011 and 2018. ...

Study investigated which characteristics of wheelchair users with spinal cord injury (SCI) are associated with greater perceived discrimination in the healthcare setting, and how such discrimination relates to 2 outcomes: pain and depressive symptoms. Data were collected between 2011 and 2016 from 410 full-time wheelchair users with SCI from 9 ...

Study compared the effects of an 8‐week isocaloric high‐protein (HP) diet versus a combined exercise regimen (Comb‐Ex) in individuals with long‐standing spinal cord injury (SCI). Twenty individuals with SCI enrolled in the University of Alabama at Birmingham SCI Model System were randomly assigned to the Comb-Ex or HP-diet group; 11 ...

Study examined the safety and effectiveness of micro-fragmented adipose tissue (MFAT) injections under ultrasound guidance for treatment of refractory shoulder pain caused by rotator cuff disease in wheelchair users with spinal cord injury (SCI). Ten wheelchair users with chronic SCI who had moderate-to-severe shoulder pain caused by refractory rotator cuff ...

Study identified the association between health behaviors and risk of all-cause and cause-specific mortality in 3,070 adults with chronic spinal cord injury (SCI). Participants were identified through records at a large rehabilitation hospital in the Southeastern United States. Behavioral data were collected by mail-in self report assessment between 1997-1998 and ...

Study assessed the accuracy of self-reported level of injury (LOI) and severity in individuals with chronic spinal cord injury (SCI) as compared with clinical examination. Twenty-eight individuals with SCI completed a 20-item survey that evaluated demographics, physical abilities, and self-reported injury level and severity. A decision-tree algorithm used responses to ...