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Burn Publications

Publication Year
2007

Symptoms of depression and anxiety as unique predictors of pain-related outcomes following burn injury

Background: The adverse consequences of burn injuries include pain and psychological distress, which show bidirectional associations. However, much of the existing research has relied on global measures of distress that do not separate distinct symptoms of anxiety and depression.Purpose: The purpose is to assess the prospective effects of anxiety ...
Publication Year
2007

Time to school reentry following burn injury is quite short

Returning to school is an important indicator of functional aptitude and emotional adjustment in school-aged patients after burn injury. Only two reports in the burn literature provide objective data on time to school re-entry. However, these analyses did not address the impact of patient and burn injury characteristics on ...
Northwest Regional Burn Model System
Publication Year
2007

Building the Research Teams of the Future: Changing the Paradigm

Abstract not available
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2007

Respiratory management of inhalation injury

Advances in the care of patients with major burns have led to a reduction in mortality and a change in the cause of their death. Burn shock, which accounted for almost 20 percent of burn deaths in the 1930s and 1940s, is now treated with early, vigorous fluid resuscitation ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2007

The microvasculature in cutaneous wound healing in the female red Duroc pig is similar to that in human hypertrophic scar and different from that in the female Yorkshire pig

The female red Duroc pig has been found to be a promising model of hypertrophic scarring. The female Yorkshire pig has been demonstrated to heal in a very different manner, more resembling human normotrophic scarring. Given these observations, we studied microvessel density, an important aspect of wound healing, in ...
Northwest Regional Burn Model System
Publication Year
2007

Hypertrophic scar, wound contraction and hyper-hypopigmentation

For decades, hypertrophic scarring, contraction, and pigment abnormalities have altered the future for children and adults after thermal injury. The hard, raised, red and itchy scars; shrunken wounds; and hyper- and hypo-pigmented scars are devastating to physical and psychosocial outcomes. The specific causes remain essentially unknown and, at present, ...
Northwest Regional Burn Model System
Publication Year
2007

Factors influencing the efficacy of virtual realtiy distraction analgesia during postburn physical therapy: Preliminary results from 3 ongoing studies

OBJECTIVE: To assess the efficacy and side effects of immersive virtual reality (VR) distraction analgesia, as well as patient factors associated with VR analgesic efficacy in burn patients who require passive range-of-motion (ROM) physical therapy (PT). DESIGN: Prospective, randomized, controlled, within-subject trials. SETTING: Regional level I burn center in ...
Northwest Regional Burn Model System
Publication Year
2007

Review of the female Duroc/Yorkshire pig model of human fibroproliferative scarring

Hypertrophic scarring after burns is an unsolved problem and remains as devastating today as it was in the 40s and it may be that the main reason for this is the lack of an accepted, useful animal model. The female, red Duroc pig was described as a model of ...
Northwest Regional Burn Model System
Publication Year
2007

The effect of oxandrolone on the endocrinologic, inflammatory, and hypermetabolic responses during the acute phase postburn

OBJECTIVE AND SUMMARY BACKGROUND DATA: Postburn long-term oxandrolone treatment improves hypermetabolism and body composition. The effects of oxandrolone on clinical outcome, body composition, endocrine system, and inflammation during the acute phase postburn in a large prospective randomized single-center trial have not been studied. METHODS: Burned children (n = 235) ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2007

Sex differences in the long-term outcome after a severe thermal injury

We have recently shown that during the acute phase, postburn female pediatric burn patients had significantly increased levels of anabolic hormones with an associated decreased hypermetabolism leading to a significant shorter intensive care unit stay compared with male patients. The aim of the present study was to determine possible ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2007

Restoration of function

Restoration of function is crucial to the performance of activities of daily living, vocational and recreational activities, as well as to community integration and psychosocial aptitude. Strategies to optimize restoration of function include both physical considerations as well as metabolic considerations that can significantly impact physical capacity. Given the ...
Publication Year
2007

Effect of insulin on the inflammatory and acute phase response after burn injury

After a severe burn, the liver plays a pivotal role by modulating inflammatory processes, metabolic pathways, immune functions, and the acute phase response. Therefore, liver integrity and function are important for recovery. A thermal injury, however, causes hepatic damage by inducing hepatic edema, fatty infiltration, hepatocyte apoptosis, and metabolic ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2007

Changes in liver function and size after a severe thermal injury

Hepatic homeostasis and metabolism are essential for survival in critically ill and severely burned patients. There is evidence that the liver undergoes hypertrophy after burn. However, the extension and the duration of liver enlargement are not known. The aim of the present study was to determine the changes in ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2007

Burn size determines the inflammatory and hypermetabolic response

BACKGROUND: Increased burn size leads to increased mortality of burned patients. Whether mortality is due to inflammation, hypermetabolism or other pathophysiologic contributing factors is not entirely determined. The purpose of the present study was to determine in a large prospective clinical trial whether different burn sizes are associated with ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2007

Effects of cessation of a structured and supervised exercise conditioning program on lean mass and muscle strength in severely burned children

OBJECTIVE: To determine whether the benefits of exercise by burned children are maintained 3 months after the exercise program is concluded. DESIGN: Randomized, controlled prospective study. SETTING: Pediatric burn hospital. PARTICIPANTS: Twenty severely burned children with a 40% or greater total body surface area burn, with main outcome measures ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2007

Outcomes after deep full-thickness hand burns

OBJECTIVE: To measure hand-specific functional performance after deep full-thickness dorsal hand burns. DESIGN: Descriptive, cross-sectional study. SETTING: The 2005 Phoenix Society's World Burn Congress, Baltimore, MD. PARTICIPANTS: Volunteer sample of burn survivors (N=32) with full-thickness dorsal hand burns with extensor mechanism involvement, who consented to participate. INTERVENTIONS: Not applicable. ...
North Texas Burn Rehabilitation Model System
Publication Year
2007

Beta-blockade in burns

A significant proportion of the mortality and morbidity of severe burns is attributable to the ensuing hypermetabolic response that typically lasts for at least 9-12 months post-injury. This is associated with impaired wound healing, increased infection risks, erosion of lean body mass, hampered rehabilitation and delayed reintegration of burn ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2007

Blood transfusions are associated with increased risk for development of sepsis in severely burned pediatric patients

transfusion of blood products in severely burned pediatric patients. Design: Retrospective, cohort study. Setting: Shriners Hospital for Children and University Hospital. Patients: Severely burned pediatric patients with >30% total body surface area (TBSA) burn. Interventions: None. Measurements and Main Results: Two hundred seventy-seven pediatric burn patients over a period ...
Pediatric Burn Injury Rehabilitation Model System
Publication Year
2007

Depression in burn reconstruction patients: Symptom prevalence and association with body image dissatisfaction and physical function

Objective: This study investigated the prevalence and the clinical correlates of symptoms of depression among burn reconstruction patients. Method: A sample of 224 burn reconstruction patients completed the Beck Depression Inventory (BDI), the SF-36 Health Survey and the Satisfaction with Appearance Scale. Results: The prevalence of at least mild ...
Johns Hopkins University Burn Injury Rehabilitation Model System
Publication Year
2007

Prevalence of major psychiatric illness in young adults who were burned as children

Objective: To determine the prevalence of major psychiatric illness in a group of young adults who suffered significant burn injury as children. Method: A total of 101 persons (58 males, 43 females), aged 21 2.6 years, 14.0 5.4 years postburn of 54% 20% total body surface area, were assessed for ...
Pediatric Burn Injury Rehabilitation Model System

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Information on this site is not meant to replace the advice of a medical professional. You should consult your health care provider regarding specific medical concerns or treatment. The contents of this site were developed under grant number 90DPKT0009 from the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR). NIDILRR is a Center within the Administration for Community Living (ACL), Department of Health and Human Services (HHS). The contents of this website do not necessarily represent the policy of NIDILRR, ACL, HHS, and you should not assume endorsement by the federal government.