Model System:

Burn

Reference Type:

JA

Accession No.:

Journal:


Critical Care Medicine

Year, Volume, Issue, Page(s):

, 35, , 579-83

Publication Website:

Abstract:

transfusion of blood products in severely burned pediatric patients. Design: Retrospective, cohort study. Setting: Shriners Hospital for Children and University Hospital. Patients: Severely burned pediatric patients with >30% total body surface area (TBSA) burn. Interventions: None. Measurements and Main Results: Two hundred seventy-seven pediatric burn patients over a period of 7 yrs (1997–2004) were included in the study, with 25 patients being septic at admission and therefore excluded. Patients were stratified according to TBSA burn and presence or absence of inhalation injury. The amounts of packed red blood cells (RBCs) and fresh frozen plasma (FFP) were recorded during hospital stay before the development of sepsis. Blood product administration was normalized for the number of surgeries and divided into two groups: high (RBCs >20/FFP >5) or low (RBCs 60% TBSA burn with inhalation injury have an 8% risk of developing sepsis in the low RBC group, which increases to 58% in the high RBC group (p

Author(s):


Jeschke, M.G., Chinkes, D.L., Finnerty, C.C., Przkora, R., Pereira, C.T., Herndon, D.N.

Participating Centers: