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  • Lori Clark

    Lori holds a bachelor’s degree in Biology and has served as a Research Technologist in UofL’s Division of Physical Medicine & Rehabilitation at FRNC since March 2012.
  • FAQ

    Frequently Asked Questions (FAQ) What does the Model Systems Knowledge Translation Center (MSKTC) do? What is "Knowledge Translation"? What is a "Model System"? How does a center earn the designation "Model System"? How can I find ...
  • Publications

    Examining driving and participation 5 years after traumatic brain injury

    Participation is often considered a primary goal of traumatic brain injury (TBI) rehabilitation, but little is known about the influence of driving on participation after TBI. The objective of this study was to examine the independent contribution of driving status to participation at 5 years post TBI, after controlling for ...
  • Publications

    Prevalence of medical and psychiatric comorbidities following traumatic brain injury

  • Publications

    Longitudinal effects of medical comorbidities on functional outcome and life satisfaction after traumatic brain injury: An individual growth curve analysis of NIDILRR Traumatic Brain Injury MS data

  • Publications

    Employment stability in the first 5 years after moderate to severe traumatic brain injury

  • Publications

    Obesity and overweight problems among individuals 1 to 25 years following acute rehabilitation for traumatic brain injury: A NIDILRR Traumatic Brain Injury Model Systems study

  • Publications

    The effects of statin treatment on outcomes following traumatic brain injury

  • Publications

    Sleep after TBI: How the TBI Model Systems have advanced the field

  • Publications

    Healthy lifestyle after traumatic brain injury: a brief narrative

    Individuals living with traumatic brain injury (TBI) are at an increased risk for developing chronic conditions such as diabetes, heart disease, and hypertension compared to the non-injured population. Furthermore, TBI-specific challenges such as physical limitations, pain, mood, and impaired cognition make it difficult to live a healthy lifestyle. Key ...
  • Publications

    Outcome prediction from post-injury resilience in patients with TBI

    PURPOSE/OBJECTIVE: The objective of the study was to evaluate the extent to which 1- and 2-year outcomes after traumatic brain injury (TBI) are predicted by resilience. Research Method/Design: This was an observational, longitudinal study of persons (n = 158) with moderate or severe TBI who completed both 1- and ...
  • Publications

    Factors associated with remission of post-traumatic brain injury fatigue in the years following TBI

    Post-traumatic brain injury fatigue (PTBIF) is a major problem in the years after traumatic brain injury (TBI), yet little is known about its persistence and resolution. The objective of the study was to identify factors related to PTBIF remission and resolution. TBI Model System registrants at five centres participated ...
  • Karen Kowalske

    Karen J. Kowalske, M.D. is a Professor in Physical Medicine in the Department of Physical Medicine and Rehabilitation at UT Southwestern Medical Center. A physical medicine and rehabilitation specialist, Dr. Kowalske has special expertise in treating patients with complicated catastrophic injuries, including burns and complex or nonhealing wounds. Dr. Kowalske is the ...
  • Publications

    Post-traumatic epilepsy associations with mental health outcomes in the first two years after moderate to severe TBI: A TBI Model Systems analysis

    Research suggests that there are reciprocal relationships between mental health (MH) disorders and epilepsy risk. However, MH relationships to post-traumatic epilepsy (PTE) have not been explored. Thus, the objective of this study was to assess associations between PTE and frequency of depression and/or anxiety in a cohort of individuals ...
  • Publications

    Longitudinal sex and stress hormone profiles among reproductive age and post-menopausal women after severe TBI: A case series analysis

    To describe hormone profiles for pre-/post-menopausal women, to monitor time to resumption of menstruation among pre-menopausal women and to describe cortisol associated LH suppression and phasic variation in other sex hormones over timeMethods and procedures: This study determined amenorrhea duration and characterized acute (days 0-7) and chronic (months 1-6) ...
  • Publications

    NIH toolbox cognition tests following traumatic brain injury: Frequency of low scores

    To apply multivariate base rate analyses to the National Institutes of Health Toolbox Cognition Battery (NIHTB-CB) to facilitate the identification of cognitive impairment in individuals with traumatic brain injury (TBI). Research Method/Design: In a multisite cross-sectional design, 158 participants who sustained a complicated mild or moderate TBI (n = ...
  • Publications

    Uncorrected versus demographically-corrected scores on the NIH Toolbox Cognition Battery in persons with traumatic brain injury and stroke

    The association between demographic characteristics and neurocognitive performance is well established; however, clinicians may have difficulty selecting when to use uncorrected versus demographically corrected scores. We compared these score types in individuals with traumatic brain injury (TBI) and stroke, on the National Institutes of Health Toolbox-Cognition Battery (NIHTB-CB). ...
  • Publications

    The Association of Rehospitalization With Participation 5 Years After Traumatic Brain Injury

    To determine whether rehospitalization during the first 2 years after moderate to severe traumatic brain injury (TBI) is associated with poor participation at 5 years post-TBI, after controlling for demographic and severity factors.
  • Publications

    Predicting long-term global outcome after traumatic brain injury (TBI): Development of a practical prognostic tool using the TBI Model Systems National Database

    For patients surviving serious traumatic brain injury (TBI), families and other stakeholders often desire information on long-term functional prognosis, but accurate and easy-to-use clinical tools are lacking. We aimed to build utilitarian decision trees from commonly collected clinical variables to predict Glasgow Outcome Scale (GOS) functional levels at 1, ...
  • Publications

    Detecting malingering in traumatic brain injury: Combining response time with performance validity test accuracy

    OBJECTIVE: The present study examined the incremental utility of item-level response time (RT) variables on a traditional performance validity test in distinguishing adults with verified TBI from adults coached to feign neurocognitive impairment. METHOD: Participants were 45 adults with moderate to severe TBI, 45 healthy adults coached to feign ...

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Information on this site is not meant to replace the advice of a medical professional. You should consult your health care provider regarding specific medical concerns or treatment. The contents of this site were developed under grant number 90DPKT0009 from the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR). NIDILRR is a Center within the Administration for Community Living (ACL), Department of Health and Human Services (HHS). The contents of this website do not necessarily represent the policy of NIDILRR, ACL, HHS, and you should not assume endorsement by the federal government.