Model System:
TBIReference Type:
JournalAccession No.:
Journal:
Brain injury
Year, Volume, Issue, Page(s):
, 30, 4, 452-461Publication Website:
https://www.ncbi.nlm.nih.gov/pubmed/26963638Abstract:
To describe hormone profiles for pre-/post-menopausal women, to monitor time to resumption of menstruation among pre-menopausal women and to describe cortisol associated LH suppression and phasic variation in other sex hormones over timeMethods and procedures: This study determined amenorrhea duration and characterized acute (days 0-7) and chronic (months 1-6) gonadotropins [luteinizing hormone and follicle stimulating hormone (LH, FSH)], sex hormones (progesterone, estradiol) and stress hormone (cortisol) profiles. Women were pre-menopausal (n = 3) or post-menopausal (n = 3). Among pre-menopausal women, menstrual cycle resolution and phase association (luteal/follicular) was monitored using self-report monthly reproductive history questionnaires. This study compared post-TBI hormone profiles, stratified by menopausal status, to hormone levels from seven controls and described 6- and 12-month outcomes for these women.
Author(s):
Ranganathan, P, Kumar, RG, Davis, K, McCullough, EH, Berga, SL, Wagner, AK