Cross-lagged panel analysis of depression and behavioral dysfunction in the first year after moderate-to-severe traumatic brain injury

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Study examined the temporal relationships between depression and behavioral dysfunction in the first year after moderate-to-severe traumatic brain injury (TBI). The authors hypothesized that 6-month depression would be the stronger contributor to 12-month depression and behavioral dysfunction in a sample of 88 adults with moderate-to-severe TBI. A structural equation modeling cross-lagged panel analysis revealed that 6-month depression had strong effects on both 12-month depression and behavioral dysfunction. This findings suggests that once an individual has clinically significant depressive symptoms after TBI, these symptoms can continue to self-perpetuate and lead to behavioral dysfunction.

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