TBI Publications

Study examined relationships between persistent hypogonadotropic hypogonadism (PHH) and long-term outcomes after severe traumatic brain injury (TBI), and determined whether subacute testosterone levels can predict PHH. Post-TBI blood samples were collected during week 1, every 2 weeks until 26 weeks, and at 52 weeks. Serum hormone levels were measured, ...

Study evaluated brain-derived neurotrophic factor (BDNF) as a biomarker for post-traumatic brain injury (TBI) depressions (PTD), cognitive impairment, and functional cognitive limitations in the first year following severe TBI. One hundred thirteen participants with TBI were evaluated for PTD using the Patient Health Questionnaire-9 (PHQ-9). Cognitive impairment using a ...

Study developed and provided initial validation of a measure for accurately determining the need for constant visual observation (CVO) in patients with traumatic brain injury (TBI) admitted to inpatient rehabilitation. An internally consistent measure of the need for CVO was developed and confirmed using Rasch analysis; the concurrent validity ...

Study investigated the prevalence of all severities of traumatic brain injury (TBI), regardless of treatment setting, and their associated negative outcomes. A statewide, population-based, random digit-dialed telephone survey assessed the lifetime history of TBI in 2,701 adult Coloradoans, using a modified version of the Ohio State University TBI Identification ...

Study examined the prevalence of depression and suicidal behavior in a large cohort of patients who sustained moderate-to-severe traumatic brain injury (TBI). Data were obtained from patients who received acute care and comprehensive rehabilitation in a TBI Model Systems-designated brain injury inpatient rehabilitation program funded by the National Institute ...

Study examined the rate of clinically significant anxiety at 1 year after moderate-to-severe traumatic brain injury (TBI), specific symptoms of anxiety, risk factors for anxiety; and associations of anxiety with other 1-year outcomes, including participation and quality of life. Participants were 1,838 individuals with moderate-to-severe TBI who were enrolled ...

Study used principal component analysis (PCA) and cluster analysis to identify the sets of markers that contribute independently to variability in cerebrospinal (CSF) inflammatory profiles after traumatic brain injury (TBI). PCA was applied to CSF inflammatory marker data collected from 114 adults with severe TBI. Using the results, groups (or ...

Study developed and internally validated preliminary prognostic regression models to predict Posttraumatic seizures (PTS) during acute care hospitalization, and at 1 year and 2 years after traumatic brain injury (TBI). Prognostic models predicting PTS during acute care hospitalization and year 1 and year 2 post-injury were developed using a ...

Article describes Project Career, a five-year, federally funded initiative to provide cognitive support technology (CST) training and career preparatory services for undergraduate college students with mild and moderate traumatic brain injuries (TBI). The goal of Project Career is to develop, implement, and test a technology-driven, long-term, and resource-rich individualized ...

Study examined resilience, defined as the ability to “bounce back” after a trauma or tragedy, at 3 months after traumatic brain injury (TBI). Participants were community-dwelling adults with moderate-to-severe TBI enrolled in the resilience module of the TBI Model System study. Of the 223 participants recruited from 5 inpatient ...

Study investigated the rates of negative outcomes associated with all severities of traumatic brain injury (TBI), treated in all settings or not treated at all, in comparison to the general population. A statewide population-based survey of 2,701 Coloradoans was conducted using the computer-assisted, modified Ohio State University TBI Identification ...

To describe hormone profiles for pre-/post-menopausal women, to monitor time to resumption of menstruation among pre-menopausal women and to describe cortisol associated LH suppression and phasic variation in other sex hormones over timeMethods and procedures: This study determined amenorrhea duration and characterized acute (days 0-7) and chronic (months 1-6) ...

Study evaluated the sensitivity and specificity of Coma Recovery Scale-Revised (CRS-R) total scores in detecting conscious awareness. Data were retrospectively extracted from the medical records of 252 patients enrolled in a specialized disorders of consciousness program. Sensitivity and specificity analyses were completed using CRS-R-derived diagnoses of minimally conscious state ...

Study explored the effect of interagency collaboration on student vocational rehabilitation outcomes in a statewide model demonstration project for youth with disabilities. Using two different measures of perceptions of collaboration among inter-agency teams, results of the study were paradoxical. The findings suggested that instrumental or task-oriented perceptions of collaboration ...

BACKGROUND: Long-term mortality may be increased following traumatic brain injury (TBI); however, the degree to which survival could be reduced is unknown. We aimed at modelling life expectancy following post-acute TBI to provide predictions of longevity and quantify differences in survivorship with the general population. METHODS: A population-based retrospective cohort ...

Study compared patient functional outcomes across Traumatic Brain Injury Model Systems (TBIMS) rehabilitation centers and identified sociodemographic, clinical, and injury characteristics that influenced patient those outcomes. Data were analyzed for 5,505 patients with traumatic brain injury (TBI) admitted to 19 TBIMS rehabilitation centers over a 10-year period (2003-2012). Functional ...

Article describes the development and calibration of the Traumatic Brain Injury Quality-of-Life (TBI-QOL), a comprehensive patient-reported outcomes (PRO) measurement system specifically for individuals with traumatic brain injury (TBI). The TBI-QOL was developed in 2 distinct phases. The initial phase focused on development of the domain structure, evaluation of extant ...

Study investigated the influence of race, gender, functional ability, and an array of preinjury, injury-related, and sociodemographic variables on life satisfaction trajectories over 10 years following moderate-to-severe traumatic brain injury (TBI). Using data from the TBI Model Systems database, a total of 3,157 individuals with TBI were included in ...

Article focuses on the first ‘‘A’’ in the Americans with Disabilities Act (ADA). That first ‘‘A’’ in the ADA’s law and policy framework is to apply to all qualified individuals with disabilities residing, working, recreating, using the web, and engaged in daily life activities with private and public organizations ...

Study evaluate sleep quality, its correlates, and the effect of telephone-based problem-solving treatment (PST) in active duty post-deployment service members with mild traumatic brain injury (mTBI). A total of 356 service members with combat-related mTBI were randomly assigned to education-only (EO) and PST groups (178 in each group). Both ...