Model System:

TBI

Reference Type:

Journal

Accession No.:

J73354

Journal:


Journal of Head Trauma Rehabilitation

Year, Volume, Issue, Page(s):

, 31, 2, 108-116

Publication Website:

Abstract:

Study examined the relationship between ratings of sleep dysfunction and serial cognitive assessments among patients with moderate-to-severe traumatic brain injury (TBI) over the first 3 week of acute neurorehabilitation. Sleep-wake cycle disturbance (SWCD) was assessed using the Delirium Rating Scale-Revised 98 and cognitive recovery was measure with the Cognitive Test for Delirium (CTD) at admission and with subsequent weekly examinations. A total of 106 participants were grouped based on the presence (SWCD+) or absence (SWCD−) of sleep dysfunction for each examination; groups were equivalent on demographic and injury variables. Individual growth curve (IGC) modeling was used to examine course of CTD performance across examinations. IGC modeling revealed a significant interaction between examination number (i.e., time) and SWCD group on total CTD score. The SWCD+ ratings on later examinations were predicted to result in lower CTD scores and greater cognitive impairment over time. These findings suggest that those with persisting sleep disturbance could be prone to different and potentially poorer courses of cognitive recovery. This study has implications for improving neurorehabilitation treatment, as targeting sleep dysfunction for early intervention may facilitate cognitive recovery.

Author(s):


Holcomb, Erin M., Towns, Stephanie , Kamper, Joel E., Barnett, Scott D., Sherer, Mark, Evan, Clea, Nakase-Richardson, Risa

Participating Centers: