Model System:

TBI

Reference Type:

JA

Accession No.:

J48771.

Journal:


Brain Injury

Year, Volume, Issue, Page(s):

, 19, 4, 239-256

Publication Website:

Abstract:

Three studies were conducted to examine the relationship between focal cortical lesion location and outcome following traumatic brain injury (TBI). Patients were grouped according to whether they had frontal only, fronto-temporal, non-frontal, or no lesions. Study 1 tested the hypothesis that focal frontal and fronto-temporal lesions would be associated with poorer performance on neuropsychological measures of executive functioning and memory at discharge from rehabilitation. Results showed that these patients performed worse in executive functioning tasks and better in constructional ability than the other patient groups. Study 2 tested the hypotheses that focal frontal and fronto-temporal lesions would be associated with poorer performance on neuropsychological measures of executive functioning and memory at 1-year post-injury and poorer behavioral and community integration outcomes. No statistically significant differences were found between patient groups. Study 3 examined the change in neuropsychological test performance over a 1-year period. Comparable test score improvement was found in all 4 patient groups. Results are consistent with previous findings and suggest that lesion location needs to be considered when implementing individual rehabilitation plans.

Author(s):


Lehtonen, S., Stringer, A. Y., Millis, S., Boake, C., Englander, J., Hart, T., High, W., Macciocchi, S., Meythaler, J., Novack, T., Whyte, J.

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