Incremental validity of neuropsychological evaluations to computed tomography in predicting long-term outcomes after traumatic brain injury

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Study evaluated the incremental utility of neuropsychological tests to computed tomography (CT) in predicting the long-term outcomes of adults with traumatic brain injury (TBI). Participants were 288 adults with mild complicated, moderate, and severe TBI who completed neuropsychological testing during inpatient status in a TBI Model Systems rehabilitation hospital, and also had follow-up data available at 1 and 2 years post injury. Predictor variables, including demographic characteristics, injury severity, CT characteristics, and neuropsychological evaluations, were regressed to outcomes of disability, life satisfaction, and employment at 1 and 2 years post injury. The results indicated that prediction of life satisfaction was not improved with the use of CT characteristics or neuropsychological tests, but prediction of return to work was improved by these variables at 2 years post injury. Neuropsychological evaluations uniquely contributed to outcome predictions of functional disability, even after considering demographic and injury severity characteristics, including information from CT. In contrast, CT characteristics were not predictive of long-term functional disability at 1 or 2 years post TBI. Taken together, the findings indicate that neuropsychological tests add unique predictive information for long-term functional outcomes after TBI.

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