Journal:Journal of Head Trauma Rehabilitation
Year, Volume, Issue, Page(s):18, 33, 1, 15-24
Study determined the comorbidities and complications that most commonly co-occur in adults aged 50 years and older with traumatic brain injury (TBI). Data were obtained from 2,134 adults 50 years of age or older with moderate/severe TBI enrolled in the TBI-Model Systems (TBI-MS) study from 2007 to 2014. International Classification of Disease–9th Revision codes, collapsed into 45 comorbidity categories, were used to classify comorbid conditions for each participant. Comorbidity prevalence estimates and trend analyses were conducted by age strata (50-54, 55-64, 65-74, 75-84, ≥85 years). A dimension reduction method, Treelet Transform, classified clusters of comorbidities that tended to co-occur. The results indicated that the 3 most commonly occurring comorbid categories were hypertensive disease (52.6 per 100 persons), other diseases of the respiratory system (51.8 per 100 persons), and fluid component imbalances (43.7 per 100 persons). Treelet Transform classified 3 clusters of comorbid codes: (1) acute medical diseases/infections, (2) chronic conditions, and (3) substance abuse disorders. This study provides valuable insight into comorbid conditions that co-occur among adults aged 50 years and older with TBI and provides a foundation for future studies to explore how specific comorbidities affect TBI recovery.