Model System:

TBI

Reference Type:

Journal

Accession No.:

J75716

Journal:


Current Addiction Reports

Year, Volume, Issue, Page(s):

, 2, 4, 273-284

Publication Website:

https://link.springer.com/article/10.1007/s40429-015-0078-3

Abstract:

Article reviews the evidence that presents the clinical picture of co-occurring traumatic brain injury (TBI) and alcohol use disorder (AUD), including the overlapping cognitive dysfunction and underlying neurobiological alterations. Recent evidence indicates that TBI can increase the risk of developing AUD. TBI and AUD share common symptoms including cognitive dysfunction. Therefore, it is of interest to better understand how reward-mediated behaviors central to alcohol addiction, such as alcohol craving, may interact with the cognitive dysfunction of TBI both at the behavioral and neurobiological level. A neuroimaging case series is used to illustrate how neural activation to alcohol cues may provide insight into the unique brain state of co-occurring mild TBI and AUD. Treatment implications for TBI and AUD and their co-occurrence are also discussed. Finally, the authors provide an overview of potential treatments for the co-occurrence of TBI and AUD.

Author(s):


Herrold, Amy A., Sander, Angelle M., Wilson, Kimberlee V., Scimeca, Lauren M., Cobia, Derin J., Breiter, Hans C.

Participating Centers: