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This research study is a collaboration between RRTBIMS, Kessler Foundation (West Orange, NJ) and TIRR Memorial Hermann (Houston, TX). The two central aims of the study are to: further establish the psychometric properties of the TBI-QOL CATs by examining their sensitivity and responsiveness to clinically meaningful changes across time and to compare the responsiveness of the TBI-QOL CATs to scores on legacy instruments already included in the TBIMS database and on anchor markers of global change to compute Minimally Important Differences.