Predictors of subclinical atherosclerosis in women with spinal cord injury

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Study determined which risk factors for cardiovascular disease (CVD) are associated with increased carotid intima-media thickness (CIMT), a common indicator of atherosclerosis, in women with spinal cord injury (SCI). One hundred twenty-two adult females with chronic SCI were evaluated. Participants were asymptomatic and without evidence of CVD. Measures collected for all participants were age, race, smoking status, level and completeness of injury, duration of injury, body mass index, serum lipids, fasting glucose, hemoglobin A1c, and ultrasonographic measurements of CIMT. After conducting univariate analyses, hierarchical multiple linear regression was conducted to predict CIMT from demographic and physiologic variables. Results indicated that several variables were significantly correlated with CIMT during univariate analyses, including glucose, hemoglobin A1c, age, and race/ethnicity; only age was significant in the hierarchical regression analysis.

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