Hydrophilic catheters versus noncoated catheters for reducing the incidence of urinary tract infections: a randomized controlled trial

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Abstract:

Objective: To test the hypotheses that hydrophilic catheters reduce the incidence of symptomatic urinary tract infections (UTIs) in persons with spinal cord injury on self-intermittent catheterization (IC). Design: Randomized controlled trial.

Setting: Community. Participants: Subjects (N=56) on IC with recurrent UTIs and who met eligibility cIitelia. Intervention: Use of hydrophilic catheters for rc. Main Outcome Measure: Symptomatic UTIs treated with antibiotics. Results: Of the 56 subjects enrolled, 45 completed the study (22 in the b-treatment group, 23 in the control group). There were 110 significant differences in demographics, including sex, between the treatment group and the controls except for more tetraplegic subjects in the control group. Seventy-one percent of the treatment group and control were men. Total number symptomatic utls treated with antibiotics was significantly smaller in tile than seventy group had at least 1 antibiotic treatment episode compared with only 50% of those with the hydrophilic catheter (P=.18). There was "no significant difference in the incidence of bacteriulia or symptomatic UTls among the 2 groups. Level of injury and years with injury were unrelated to symptomatic UTIs, but being female increased the risk of UTIs.

Conclusions: although there was do difference in the number of symptomatic utls groups hydrophilic catheter usage associated with reduced numbers treated utis as compared standard non-hydrophilic catheters persons spinal cord injnry who used self-ic however study is limited by a small sample size. Women on self-ie were more likely to develop regardless type suggesting that benefits lublication may be important men.

Key words: rehabilitation injuiies urinary catheterization tract infections.

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