Hydrophilic catheters versus noncoated catheters for reducing the incidence of urinary tract infections: a randomized controlled trial

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Abstract:

Objective: To test the hypotheses that hydrophilic catheters reduce the incidence of symptomatic urinary tract infections (UTIs) in persons with spinal cord injury on self-intermittent catheterization (IC). Design: Randomized controlled trial.
Setting: Community. Participants: Subjects (N=56) on IC with recurrent UTIs and who met eligibility cIitelia. Intervention: Use of hydrophilic catheters for rc. Main Outcome Measure: Symptomatic UTIs treated with antibiotics. Results: Of the 56 subjects enrolled, 45 completed the study (22 in the b-eatrnent group, 23 in the coutrol group). There were 110 significant differences in demographics, including sex, between the treatment group and the controls except for more tetraplegic subjects in the control group (P<.05 seventy-one="" percent="" of="" the="" treatment="" group="" and="" control="" were="" men.="" total="" number="" symptomatic="" utls="" treated="" with="" antibiotics="" was="" significantly="" smaller="" in="" tile="" than="" seventy=""> group had at least 1 antibiotic treatment episode compared with only 50% of those with the hydrophilic catheter (P=.18). There was "no significant difference in the incidence of bacteriulia or symptomatic UTls among the 2 groups. Level of injury and
years with injury were unrelated to symptomatic UTIs, but being female increased the Iisk of UTls (P<.ol conclusions:="" although="" there="" was="" do="" difference="" in="" the="" number="" of="" symptomatic="" utls="" groups="" hydrophilic="" catheter="" usage="" associated="" with="" reduced="" numbers="" treated="" utis="" as="" compared="" standard="" nonhydrophilic="" catheters="" persons="" spinal="" cord="" injnry="" who="" used="" self-ic="" however="" study="" is="" limited="" by="" a="" small="" sample="" size.="" women="" on="" self-ie="" were="" more="" likely="" to="" develop="" regardless="" type="" suggesting="" that="" benefits="" lublication="" may="" be="" important="" men.="" key="" words:="" rehabilitation="" injuiies="" urinary="" catheterization="" tract="" infections.="">

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