Journal:Journal of Neuroscience
Year, Volume, Issue, Page(s):15, 35, 46, 15466-15476
Humans shape their hands to grasp, manipulate objects, and to communicate. Nonhuman primate studies have shown that visual and motor properties for grasps can be derived from cells in the posterior parietal cortex (PPC). This study showed for the first time how single neurons in the PPC of humans are selective for particular imagined hand shapes independent of graspable objects. Findings indicate that motor imagery to shape the hand can be successfully decoded from the PPC by implementing a version of the Rock-Paper-Scissors game and its extension Rock-Paper-Scissors-Lizard-Spock. By simultaneous presentation of visual and auditory cues, researchers can discriminate motor imagery from visual information and show differences in auditory and visual information processing in the PPC. These results also demonstrate that neural signals from human PPC can be used to drive a dexterous cortical neuroprosthesis.