Model System:

TBI

Reference Type:

Journal article

Accession No.:

J87443

Journal:

Journal of Head Trauma Rehabilitation

Year, Volume, Issue, Page(s):

, 36, 5, 310-327

Publication Website:

Abstract:

Study assessed the scope of the literature on receipt of and use prescription and nonprescription opioids among individuals with traumatic brain injury (TBI). Four electronic databases were search for relevant studies. Multiple reviewers screened abstracts and full-text articles for eligibility. In total, 771 abstracts were screened, 183 underwent full-text review, and 21 studies met the eligibility criteria. Relevant content was independently extracted, including authors, design, sample identification and data sources, TBI severity, TBI assessment, opioid assessment, study population, military affiliation, comparison groups, date of data collection, and summary of findings. The included studies were published between 1987 and 2019; most data were collected prior to 2015. The majority utilized administrative and electronic medical record data from the Department of Veterans Affairs and retrospective cohort designs, and most focused on prescription opioids. There were no studies evaluating interventions to reduce use of opioids in TBI populations. Preliminary findings suggest that prescription opioid receipt is strongly related to psychological symptoms, including comorbid depression, anxiety, and posttraumatic stress disorder. Overall, this review found that despite increased awareness of opioid receipt and use following TBI, there is limited scientific examination of this issue. Future studies should include more varied patient populations as well as evaluate interventions to reduce opioid use following TBI.

Author(s):

Starosta, Amy J. Adams, Rachel S. Marwitz, Jennifer H. Kreutzer, Jeffrey Monden, Kimberley R. |Dams O'Connor, Kristen |Hoffman, Jeanne|

Participating Centers: