Efficacy of the diabetes prevention program group lifestyle balance program modified for individuals with TBI (GLB-TBI): Results from a 12-month randomized controlled trial

Model System:

TBI

Reference Type:

Journal article

Accession No.:

J89822

Journal:

Annals of Behavioral Medicine

Year, Volume, Issue, Page(s):

2022 , , ,

Publication Website:

Abstract:

Study assessed the efficacy of the Diabetes Prevention Program Group Lifestyle Balance for TBI (GLB-TBI) weight-loss intervention compared to an attention control for primary (weight-loss) and secondary health outcomes; of individuals after traumatic brain injury (TBI). The study also examined participant compliance with the GLBTBI and investigated whether compliance is associated with improved outcomes. Fifty-seven individuals with moderate-to-severe TBI, age 18–64 years, ≥6 months postinjury, and body mass index of at least 25 kilograms per meter squared were randomized to a 12-month, 22-session GLB-TBI intervention or attention control condition. Weight-loss, anthropometric, biomarkers, and patient-reported outcomes were collected at baseline, 3, 6, and 12 months. The GLB-TBI group lost 17.8 pounds (7.9 percent) over the 12-month program and the attention control group lost 0 pounds. The GLB-TBI group had significant improvements in diastolic blood pressure, triglycerides, and high-density lipoprotein cholesterol. GLB-TBI attendance was 89.6 percent and weekly self-monitoring of diet and activity was 68.8 percent. Relative to baseline, the GLB-TBI compliant group (≥80 percent attendance; ≥85 percent self-monitoring) had a statistically significant decrease in weight at each assessment, the noncompliant group had a significant decrease between 6 and 12 months, with no change in weight in the attention control group. The findings suggest for adults with TBI who are overweight or obese, participation in the GLB-TBI can significantly reduce weight and metabolic risk factors and increase self-reported habits for diet and exercise.

Author(s):