Model System:


Reference Type:

Journal article

Accession No.:



Clinical Journal of Pain

Year, Volume, Issue, Page(s):

, 36, 4, 281-288

Publication Website:


Study developed a scale that can be used to measure the intensity of nociception in patients with traumatic brain injury (TBI) who are unable to provide subjective pain reports. Assessment of nociception aids diagnosis and helps balance reduction in suffering with avoidance of sedating medications. Existing assessment methods confound patients' level of consciousness with the intensity of nociception, complicating pain assessment as consciousness evolves. The authors sought to develop a measure of nociception that is independent of the level of consciousness. Fifteen behavioral and physiological items likely to be sensitive to nociception were identified. One hundred fifty-seven noncommunicative patients with TBI were rated in 4 different activities predicted to modulate nociception, on each of 2 days, one randomly chosen for acetaminophen administration. The level of consciousness and level of agitation were also measured. Rasch analysis was used to assess item fit to an underlying dimension of nociception. Five items that demonstrated poor fit to the dimension were removed. The 10 remaining items demonstrated acceptable fit. Scores were significantly influenced by activity and analgesic treatment and were largely independent of measures of consciousness and agitation. Accurate scores could be obtained in about 10 minutes and were robust to missing data. The results indicate that the Brain Injury Nociception Assessment Measure (BINAM) is reliable and feasible to administer. It can assess the intensity of nociception largely independent of the level of consciousness. Further research is warranted on the impact of BINAM use on the care of patients with severe TBI.


Whyte, John |Poulsen, Ingrid |Ni, Pengsheng |Eskildsen, Marianne |Guldager, Rikke|

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