Model System:

SCI

Reference Type:

Journal article

Accession No.:

J85829

Journal:

American Journal of Physical Medicine and Rehabilitation

Year, Volume, Issue, Page(s):

, 99, 12, 1138-1144

Publication Website:

Abstract:

Study explored feasibility of smartphone-based digital phenotyping methods to examine depression and its relationship to psychosocial well-being indicators after spinal cord injury (SCI). A smartphone research platform obtained smartphone sensor and survey data among 43 community-living adult wheelchair users with SCI. Weekly measurements for 4 months included the Patient Health Questionnaire 8, the Spinal Cord Injury–Quality of Life Satisfaction with and ability to participate in social roles and activities, global positioning system–derived community mobility metrics, health conditions, and physical activity. Study retention was higher among individuals offered financial incentives (78 percent) compared with participants enrolled before incentives (50 percent). Participants who dropped out more commonly had nontraumatic or acute SCI, were older, and had less satisfaction, and lower participation in social roles and activities. Among 15 individuals with complete data, half had 1 week or more of mild depression. Those with depression had frequent health issues, less satisfaction, and lower participation in social roles and activities. Those without depression experienced increased social engagement over time. Average community mobility was similar across depression groups. Relationships were typically in-phase but also varied by individual. Findings suggest that smartphone-based digital phenotyping of psychosocial well-being after SCI is feasible but not without attrition challenges. Individual differences in depression patterns highlight the clinical utility of scaling these methods.

Author(s):

Mercier, Hannah W. Hamner, Jason W. Torous, John |Onnela, Jukka P. Taylor, J. Andrew|

Participating Centers: