The occurrence of single and multiple organ dysfunction in pediatric electrical vs. other thermal burns

Model System:

Burn

Reference Type:

Journal article

Accession No.:

J81089

Journal:

Journal of Trauma and Acute Care Surgery

Year, Volume, Issue, Page(s):

2017 , 82, 5, 946-951

Publication Website:

Abstract:

Study compared the incidence and severity of single organ failure (SOF) and multiple organ failure (MOF) as well as other complications between electrically and thermally burned children. A total of 288 pediatric patients, 96 with electrical burns (EB) and 192 with other thermal burns (CTR) were analyzed. Demographic data; length of hospitalization; and number and type of operations, amputations, and complications were statistically analyzed. The incidence of SOF and MOF was assessed using the DENVER2 classification in an additive mixed model over time. Compound scores and organ-specific scores for lung, heart, kidney, and liver were analyzed. Serum cytokine expression profiles of both groups were also compared over time. Significance was accepted at p < 0.05. Both groups were comparable in age, percent total body surface area burned, and length of hospitalization. The percentage of high-voltage injury in the EB group was 64 percent. The incidence of MOF was lower in the EB group (2.1 percent) than the CTR group (10.4 percent). The incidence of SOF was comparable between groups. Incidence of pulmonary failure was comparable in both groups, but incidence of inhalation injury was significantly higher in the CTR group. Patients in the EB group had more amputations, major amputations, and combined major amputations. Mortality was comparable between the groups. Serum cytokine expression profiles were also comparable between the groups.

Author(s):