The impact of comorbid conditions on long-term patient-reported outcomes from burn survivors

Model System:

Burn

Reference Type:

Journal article

Accession No.:

J85047

Journal:

Journal of Burn Care And Research (formerly Journal of Burn Care & Rehabilitation)

Year, Volume, Issue, Page(s):

2020 , 41, 5, 956-962

Publication Website:

Abstract:

Study evaluated the association between specific comorbidities and long-term, patient-reported health-related quality of life measures after burn injury. A unique dataset of patient-reported outcomes was generated by merging the Harborview Medical Center Trauma Registry and the Burn Model Systems National Database. The merged dataset included 493 adult participants. Demographic data, injury-specific information, and the prevalence of 20 comorbidities were systematically documented. The impact of comorbidities on responses to Short Form-12/Veterans RAND 12 (SF/VR-12) health surveys at 6, 12, and 24 months postinjury was evaluated with generalized linear models. Median age was 46 years and 72 percent were male. Median burn size was 14 percent of total body surface area burned. Seventy percent of participants had ≥1 comorbidity. SF/VR-12 mental component summary scores at 6 and 12 months postinjury were negatively associated with mental illness. SF/VR-12 physical component summary (PCS) scores were negatively associated with smoking, diabetes, and alcohol use disorder at 6-month follow-up. Twelve-month SF/VR-12 PCS scores were negatively associated with prior trauma admission and diabetes. Twenty-four-month SF/VR-12 PCS scores were negatively associated with mental illness. Smoking, alcohol use disorder, and diabetes were associated with lower PCS scores 6 months after injury; diabetes persisted as a negatively associated covariate at 12 months. Mental component summary scores were negatively associated with mental illness 6 and 12 months postinjury. Integrated models of post-discharge comorbidity management need to be tested in burn patients.

Author(s):