Model System:

Burn

Reference Type:

JA

Accession No.:

Journal:


Pain

Year, Volume, Issue, Page(s):

, 138, 3, 497-506

Publication Website:

Abstract:

Both cross-sectional studies of chronic pain and sleep deprivation experiments suggest a bidirectional relationship between sleep and pain. Few longitudinal studies, however, have assessed whether acute-insomnia following traumatic injury predicts the development of persistent pain. We sought to evaluate: 1) whether in-hospital insomnia independently predicts long-term pain after burn injury and 2) whether in-hospital pain predicts future insomnia symptoms. We analyzed data on 333 subjects hospitalized for major burn injury (72.7% male; mean age = 41.1 years ±14.5) who were participating in the multi-site, Burn Model System project. Subjects completed measures of health, function (SF-36), and psychological distress (Brief Symptom Inventory) while in-hospital, at 6, 12, and 24 months after discharge. Participants were categorized as either having or not having sleep onset insomnia at discharge. Linear mixed effects analyses revealed that persons reporting insomnia at discharge (40.5%) had significantly decreased improvement in pain and increased pain severity during long-term follow up (p<.001 more="" severe="" pain="" during="" the="" week="" preceding="" hospital="" discharge="" time="" from="" injury="" lack="" of="" college="" education="" and="" older="" age="" also="" contributed="" independent="" effects="" on="" chronic="" in="" a="" reciprocal="" model="" predicted="" increased="" rates="" long-term="" sleep="" onset="" insomnia.="" in-hospital="" insomnia="" preburn="" mental="" health="" symptoms="" were="" highly="" significant="" predictors="" this="" study="" provides="" support="" for="" prospective="" interaction="" between="" pain.="" future="" work="" should="" ascertain="" whether="" treatment="" acute="" can="" prevent="" or="" minimize="">

Author(s):


Smith, M. T., Klick, B., Kozachik, S., Edwards, R. R., Holavanahalli, R., Wiechman, S., Blakeney, P., Lezotte, D., Fauerbach, J. A.

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