Short Tilte:Long-term survival after traumatic brain injury: A population-based analysis
Year, Volume, Issue, Page(s):04, 19, 1, 37-43
Article presents an analysis of long-term survival among a random sample of Americans who experienced traumatic brain injury (TBI). Both 30-day and long-term survival were analyzed for moderate-to-severe and mild TBI cases separately. Review of medical records identified 1,448 confirmed incident cases; 164 were moderate to severe and 1,284 were mild. The estimated 30-day case fatality rate was 29 percent for moderate-to-severe cases and 0.2 percent for mild cases. Comparison of observed mortality with expected mortality revealed a risk ration of 5.29 for moderate-to-severe cases and 1.33 for mild cases. Proportional hazards modeling showed the adjusted hazard of all-cause mortality for moderate-to-severe cases relative to mild cases was 5.18 within 6 months of the event and 1.04 for the remaining follow-up period. Findings indicate that people with mild TBI exhibit a small but statistically significant reduction in long-term survival compared to the general population. The case fatality rate for people with moderate-to-severe TBI is very high, but among 6-month survivors, long-term survival is similar to that for people with mild TBI.