Model System:

Burn

Reference Type:

JA

Accession No.:

Journal:


Ann. Surg.

Year, Volume, Issue, Page(s):

, 244, 1, 121-130

Publication Website:

Abstract:

Introduction:
Recent evidence suggests that female severely burned children have higher endogenous anabolic hormone levels and a shorter ICU stay compared with males. The purpose of this study was to analyze the influence of age and gender on resting energy expenditure (REE) in severely burned children from acute hospitalization through 12 months postburn.
Methods:
A total of 100 pediatric patients with >40% total body surface area (TBSA) burn were enrolled in a prospective study and followed by indirect calorimetry measurements. The REE was expressed as actual REE kcal/d, percent of predicted REE, and REE/ body mass index (BMI). Statistical analysis was performed by Student t test and one-way ANOVA for repeated measures. Significance was accepted at P Results:
The measured REE was significantly higher in males versus females at all time points (P 10 years of age was significantly higher in males compared with females (P Conclusion:
Data show that female children exert a decreased hypermetabolic response compared with male children, which may improve burn outcomes in females.

Author(s):


Mlcak, R.P., Jeschke, M.G., Barrow, R.E., Herndon, D.N.