Short Tilte:Age differences in inflammatory and hypermetabolic postburn responses
Year, Volume, Issue, Page(s):08, 121, 3, 497
OBJECTIVE: The aim of this study was to identify contributors to morbidity and death in severely burned patients 4 years of age lost body weight and lean body mass. The inflammatory cytokine profile showed no differences between the 3 age groups, whereas liver size increased significantly in the 10- to 18-year-old group and was lowest in the 0- to 3.9-year-old group. Acute-phase protein and cortisol levels were significantly decreased in the toddler group, compared with the older children. Cardiac data indicated increased cardiac work and impaired function in the toddler group, compared with the other 2 age groups. CONCLUSIONS: Increased mortality rates for young children are associated with increased cardiac work and impaired cardiac function but not with the inflammatory and hypermetabolic responses.