SCI Publications

Study assessed the effects of gene expression or intracellular signaling in paralyzed muscles of men with long-standing spinal cord injury (SCI). Specifically, it examined the expression of genes (TNFαR, TNFα, IL-6R, IL-6, TWEAK, TWEAK R, atrogin-1, and MuRF1) and abundance of intracellular signaling proteins (TWEAK, TWEAK R, NF-κB, and ...

Study examined the relationship between time to rehabilitation after spinal cord injury (SCI) and rehabilitation outcomes at discharge and 1-year postinjury. Participants were 3,937 patients who experienced traumatic SCI between 2000 and 2014, were 18 years or older, and were admitted to a Spinal Cord Injury Model Systems center ...

Study investigated whether age, pinprick scores in the lower extremities, and neurologic severity of injury influence recovery of ambulation in people with motor complete, sensory incomplete spinal cord injury (SCI) 1 year after initial injury. This retrospective analysis examined 249 subjects with American Spinal Injury Association Impairment Scale (AIS) ...

Study used previous research data to determine appropriate roughness thresholds to characterize whether pedestrian pathways poses a comfort or health risk to wheelchair users. A previously published study investigated the correlation between the pathway roughness index (PRI) and whole body vibration (WBV) exposure to wheelchair users. The results of ...

Study investigated the contribution of residential neighborhood characteristics to race disparities in participation among community-living adults with chronic spinal cord injury (SCI). Survey data from the SCI Model Systems (SCIMS) database were linked with residential characteristics derived from national survey and spatial data to assess the contribution of social, ...

Study compared the measurement properties and responsiveness to change of the Patient Health Questionnaire-9 (PHQ-9), the Hopkins Symptom Checklist-20 (HSCL-20), and the Hamilton Depression Rating Scale (HAM-D) in people with spinal cord injury (SCI) diagnosed with major depressive disorder (MDD). This was a secondary analysis of depression symptoms measured at ...

Study assessed patient perspectives or preferences on when and how professionals should deliver news to patients regarding poor prognosis for neurological recovery after severe (neurologically complete) traumatic spinal cord injury (SCI). Sixty subjects with a motor-complete SCI for at least 3 months were recruited from three geographically different acute ...

Study assessed the prevalence of bowel-related complications in people with spinal cord injury (SCI) and identified the factors associated with constipation and incontinence as well as overall bowel dysfunction. A total of 291 subjects who incurred traumatic SCI with resultant neurogenic bowel were evaluated. Constipation, bowel incontinence, and neurogenic ...

STUDY DESIGN: Prospective, randomized, controlled parallel group trial with single-blinded data analysis. OBJECTIVES: To determine the safety and efficacy of higher (20 ml kg(-1) ideal body weight (IBW)) vs standard (10 ml kg(-1) IBW) tidal volumes (Vt) for patients with sub-acute traumatic tetraplegia during ventilator weaning using a 14-day (minimum) ...

Study examined the construct of loneliness and its correlates in people with spinal cord injury (SCI), assessed the reliability and validity of the 3-item Loneliness Scale, and evaluated the unique impact of loneliness on psychological health. Data were collected from 175 people with SCI who participated in Spinal Cord ...

Study evaluated the effectiveness of telephone counseling (TC) in reducing medical complications and health care utilization and improving psychosocial outcomes during the first year after spinal cord injury (SCI) rehabilitation. A total of 168 patients participated in a single-site, single-blind, randomized controlled trial comparing usual care plus TC with ...

Article provides information related to pregnancy, labor, and delivery for women with spinal cord injury who are pregnant or considering having a baby.

Study explored women’s experiences of living with spinal cord injury (SCI) and neurogenic bladder and bowel (NBB), a chronic condition hindering the functioning and quality of life of people with SCI. Secondary analysis of semi-structured interviews from a larger qualitative study of 50 women with SCI was conducted. Transcripts ...

Study assessed the relationship between measures of activity with dyspnea and satisfaction with life in chronic spinal cord injury (SCI). Between July 2012 and March 2015, 347subjects with traumatic SCI ≥1 year after injury who used a manual wheelchair or walked with or without an assistive device reported hours ...

Study evaluated the psychometric properties of the Spinal Cord Injury-Functional Index/Assistive Technology (SCI-FI/AT) short forms (SFs) in the domains of basic mobility, self-care, fine motor function, and ambulation based on internal consistency, with specific SFs for people with paraplegia and tetraplegia. The study also examined correlations between SFs and ...

Study assessed clinical and demographic characteristics associated with change in bone density over a mean of 21 months in 152 men and women with chronic spinal cord injury (SCI) who were enrolled in the Fracture Risk after SCI (FRASCI) study. The association between statin use and bone loss following ...

Design: Convenience cross-sectional sample survey. Setting: Nine Spinal Cord Injury Model Systems Centers. Participants: People with spinal cord injury who use a wheelchair >40h/wk (N=591). Interventions: Not applicable. Main outcome measures: Number of repairs needed and resulting adverse consequences, number and types of repairs completed, and location where main ...

Study investigated the effects of transcranial direct current stimulation (tDCS) on the nociceptive response and on interleukin-1 beta (IL-1β), interleukin-10 (IL-10), and tumor necrosis factor alpha (TNF-α) levels in central nervous system (CNS) structures of rats with neuropathic pain (NP). tDCS is a non-invasive method of cerebral stimulation and ...

Study developed mathematical models for predicting level of independence with specific functional outcomes 1 year after discharge from inpatient rehabilitation for spinal cord injury (SCI). Specifically, the study compared the accuracy and performance of statistical analyses using artificial neural networks (ANNs) and logistic regression methods to estimate longer-term ambulation ...

Study identified behaviors associated with the management of neurogenic bowel and bladder among individuals with chronic spinal cord injury (SCI) and explored whether relationships exist between the performance of those behaviors and outcomes related to health and quality of life (QOL). A survey developed to collect self-report information about ...