Lead Center:Midwest Regional Spinal Cord Injury Care System
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The objective of this research project is to determine the effect of a 5-day intervention with daily acute intermittent hypoxia (AIH) therapy, either alone or coupled with task-specific training, on upper extremity function in individuals with chronic SCI, with some residual intrinsic hand muscle activation.
Hypothesis: A combinatorial intervention with AIH therapy + upper limb training will be significantly more effective in improving hand function, compared to individual treatments alone.
Specific Aim: To test this hypothesis, we will determine the impact of combined daily AIH therapy and high-repetition task-specific upper extremity training on arm strength and hand dexterity in persons with tetraplegia.