Burn Publications

Study examined the feasibility of a computerized, burn-specific patient-reported outcome measures, the Young Adult Burn Outcome Questionnaire (YABOQ), with real-time benchmarking feedback in a burn outpatient practice. The YABOQ was redesigned for formatting and presentation purposes, transcribed to a computerized format, and administered to young adult burn survivors via ...

Study compared long-term functional outcome between severely burned children who either participated or did not participate in a 12-week exercise program. A total of 125 severely burned children (mean age 12 years) who received no long-term anabolic drugs chose between a voluntary exercise program (EX-group) and no exercise (NoEX-group) ...

Study examined self-reported Satisfaction With Life Scale (SWLS) scores in a longitudinal, multicenter cohort of survivors of major burns and identified risk factors associated with SWLS scores are identified. The SWLS is a validated 5-item instrument with items rated on a 1-7 Likert scale. Data from the Burn Model ...

Article describes the development and validation of a conceptual framework for understanding the social impact of burn injuries in adults, based on the International Classification of Functioning, Disability and Health (ICF). A comprehensive literature review and consultations with clinical experts and burn survivors were performed to identify social life ...

Article reviews the current understanding of the pathophysiology of smoke inhalation injury, the best evidence-based treatments, and challenges and future directions in diagnostics and management. Smoke inhalation injury is a serious medical problem that increases morbidity and mortality after severe burns. Despite recent advances in critical care and the ...

Improvements in acute burn care have enabled patients to survive massive burns that would have once been fatal. Now, up to 70 percent of patients develop hypertrophic scars after burns. Patients with these massive burns have extensive scarring and contractures, itch, and pain. They are dissatisfied with their appearance ...

Study assessed the effects of exercise combined with whole-body vibration (WBV) on bone mass, lean mass (LM), and muscle strength in children recovering from burns. Nineteen children with ≥30 percent total body surface area (TBSA) burns were randomly assigned to a 6-week exercise regimen either alone (EX) or in ...

Study compared cardiac output (CO) measurements performed in severely burned children using the transpulmonary thermodilution (TPTD) with the PiCCO (Pulse index Continuous Cardiac Output) system or transthoracic echocardiography (TTE). Fifty-four severely burned children were studied. Outcomes were compared using t-tests, multiple linear regression, and a Bland-Altman plot. An analysis ...

Article discusses the psychometric properties and clinical utility of the Burn Outcome Questionnaires (BOQs). The BOQs are currently the most well-studied and clinically developed patient-reported outcome measures for use in children with burn injuries. There are currently four separate BOQ instruments: (1) the BOQ0–5, administered to the parents of ...

This study developed a scoring system that stratifies burn patients at the time of hospital admission according to risk of developing heterotopic ossification (HO), the development of abnormal bone in the soft tissue. HO in burns is an uncommon but severely debilitating problem with a poorly understood mechanism and ...

Study investigated whether the administration of oxandrolone, a synthetic testosterone derivative, will improve pulmonary function in burned pediatric subjects. Lung volumes and spirometry were assessed in 54 burned subjects during scheduled outpatient clinic visits 6 months post burn. The subjects were previously randomized to either the control arm or ...

Study investigated whether administration of oxandrolone for 2 years yields greater effects on bone mineral content (BMC), bone mineral density (BMD), and growth in 119 hospitalized children with severe burn injury (30 percent or more total body surface area burned). Eighty four patients were randomized to the control group, ...

Study evaluated the efficacy of a 12-week community-based exercise training rehabilitation program (COMBEX) in improving lean mass, muscle strength, and aerobic capacity in children with severe burns. Thirty-four pediatric patients (aged 7–18 years) with burns covering 30 percent or more of their total body surface area (TBSA) were randomized ...

Study investigated whether the combined administration of oxandrolone and propranolol attenuates growth arrest and improves the rate of growth, compared to the administration of oxandrolone or propranolol alone, in severely burned children. In this prospective, randomized study of 612 burned children (males between the ages of 0.5 and 14 ...

Study explored how hypermetabolism contributes to muscle wasting in burn patients. It was hypothesized that oxidative stress, cytosolic protein degradation, and mitochondrial stress as a result of hypermetabolism contribute to postburn muscle cachexia. Fourteen patients with burns covering more than 30 percent of their total body surface area were ...

Study determined the temporal relationship between burn trauma and mitochondrial function in murine skeletal muscle local to and distal from burn wounds. Male mice (8-10 weeks old) were burned by submersion of the dorsum in water to create a full thickness burn on approximately 30 percent of the body. ...

Study examines the incidence and severity of contractures in a large, multicenter, pediatric burn population and determined the associated risk factors for the development of contractures. Data from the National Institute on Disability and Rehabilitation Research Burn Model System database, for pediatric (younger than 18 years) burn survivors from ...

Study documents the long-term musculoskeletal complications following major burn injury. This is a cross-sectional descriptive study that includes a one-time evaluation of 98 burn survivors (mean age = 47 years; mean total body surface area burned = 57 percent; and mean time from injury = 17 years.) A comprehensive ...

Article provides a brief overview of the purpose of and information included in the Burn Injury Model System (BMS) National Database. The BMS collects informative data on both adult and pediatric survivors following a major burn. It also collects information on return to work, school, and participation in the ...